Results 291 to 300 of about 1,015,895 (316)
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The spinning of randomized controlled trials
Journal of Vascular Surgery, 2022Frank J, Veith, Kosmas I, Paraskevas
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Beyond randomized, controlled trials
Current Opinion in Critical Care, 2004Most critical care physicians believe that randomized, controlled trials provide the best available evidence. This review contends that the importance of randomized, controlled trials was overemphasized and that they do not add more to knowledge and practice than physiologic and observational studies.
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The Design of Randomized Controlled Trials
2008Today's clinical practice relies on the application of well-designed clinical research, the gold standard test of an intervention being the randomized controlled trial. Principles of the randomized controlled trial include emphasis on the principal research question, randomization, and blinding; definitions of outcome measures, inclusion and exclusion ...
Bryan M, Curtis +2 more
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The ethics of randomized controlled trials
European Journal of Surgical Oncology (EJSO), 1995The contemporary ethical paradigm within which all clinical research is conducted is based on the four principles: respect for autonomy, beneficence and non-maleficence and justice. The fierce debate that often rages around the conduct of clinical trials results from the disagreement about the scope of application of these categorical imperatives and ...
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Randomized Controlled Trials 1: Design
2015Today's clinical practice relies on the application of well-designed clinical research, the gold standard test of an intervention being the randomized controlled trial. Principles of the randomized control trial include emphasis on the principal research question, randomization, blinding; definitions of outcome measures, of inclusion and exclusion ...
Bryan M, Curtis +2 more
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When to randomize patients in a randomized controlled trial?
Fertility and SterilityThe timing of randomization should be considered carefully in the context of each trial because it has implications for the particular research question answered. In most instances, randomization should be delayed until as close as practically possible to the moment of intervention.
Sarah Lensen +3 more
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Increasing power in randomized controlled trials*
Critical Care Medicine, 2009Conducting adequately powered randomized controlled trials in critically ill patients is a challenging business. Without even starting to consider issues of ethics and consent, the critical care researcher is limited by the relatively small and extremely heterogeneous available patient population.
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Orthopaedic Nursing, 2008
Randomized controlled trials, also known as true experiments or intervention studies, are considered to be the gold standard research design for demonstrating a cause-and-effect relationship between an intervention and an outcome. This article will describe key methodological concepts that make the randomized controlled trial this gold standard ...
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Randomized controlled trials, also known as true experiments or intervention studies, are considered to be the gold standard research design for demonstrating a cause-and-effect relationship between an intervention and an outcome. This article will describe key methodological concepts that make the randomized controlled trial this gold standard ...
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