Effects of auriculotherapy on blood pressure levels in hypertensive adults and older adults
Objective: to evaluate the effect of auriculotherapy on blood pressure and well-being parameters in hypertensive adults and older adults. Methods: a quasi-experimental, before-and-after study of a group undergoing a course of auriculotherapy. The initial
Victor Hugo Martins Santos+5 more
doaj +1 more source
The efficacy of glucocorticoid for treatment of acute spinal cord injuries remains a controversial topic. Differing medical societies have issued conflicting recommendations in this regard.
Vincent J. Cheung+4 more
semanticscholar +1 more source
A Randomized Controlled Trial on the Hemostasis of Femoral Artery Using Topical Hemostatic Agent [PDF]
Objective: Evaluation of the effect of using a topical hemostatic agent named “ChitoHem®” on different factors on patients undergoing diagnostic coronary angiography. Methods: The present blind, randomized, controlled study included 124 patients randomly divided into 2 groups.
Soheila S. Kordestani+8 more
openaire +3 more sources
Improving randomized controlled trial analysis via data-adaptive borrowing [PDF]
In recent years, real-world external controls have grown in popularity as a tool to empower randomized placebo-controlled trials, particularly in rare diseases or cases where balanced randomization is unethical or impractical. However, as external controls are not always comparable to the trials, direct borrowing without scrutiny may heavily bias the ...
arxiv
Subgroup identification in individual patient data meta-analysis using model-based recursive partitioning [PDF]
Model-based recursive partitioning (MOB) can be used to identify subgroups with differing treatment effects. The detection rate of treatment-by-covariate interactions and the accuracy of identified subgroups using MOB depend strongly on the sample size. Using data from multiple randomized controlled clinical trials can overcome the problem of too small
arxiv +1 more source
Selective serotonin reuptake inhibitors (SSRIs) for stroke recovery. [PDF]
BACKGROUND: Stroke is the major cause of adult disability. Selective serotonin reuptake inhibitors (SSRIs) have been used for many years to manage depression.
Bailey, Matthew+5 more
core +1 more source
Treating Depression with Botulinum Toxin: A Pooled Analysis of Randomized Controlled Trials
Introduction: Botulinum toxin A (BTA) injection into the glabellar region is currently being studied as a treatment for major depressive disorder (MDD). Here we explore efficacy data of this novel approach in a pooled analysis.
M. Magid+9 more
semanticscholar +1 more source
Maternal Obesity and Fetal Macrosomia: An Integrative Review of the Literature Regarding Interventions [PDF]
Research suggests pre-pregnancy obesity is associated with an increased risk of macrosomia in the newborn. Since women are expected to gain weight during pregnancy, the standard recommendation of weight loss for obesity is not ideal for this population ...
Stalcup, Charity
core +1 more source
The content and delivery of psychological interventions for perinatal depression by non-specialist health workers in low and middle income countries: a systematic review. [PDF]
Psychological interventions delivered by non-specialist health workers are effective for the treatment of perinatal depression in low- and middle-income countries.
Ahmad, Ikhlaq+7 more
core +1 more source
Prognostic Adjustment with Efficient Estimators to Unbiasedly Leverage Historical Data in Randomized Trials [PDF]
Although randomized controlled trials (RCTs) are a cornerstone of comparative effectiveness, they typically have much smaller sample size than observational studies because of financial and ethical considerations. Therefore there is interest in using plentiful historical data (either observational data or prior trials) to reduce trial sizes.
arxiv