Results 121 to 130 of about 346,597 (387)

A guide to performing a peer review of randomised controlled trials [PDF]

, 2015
Peer review of journal articles is an important step in the research process. Editors rely on the expertise of peer reviewers to properly assess submissions.
Del Mar, Chris, Hoffmann, Tammy C.
core   +2 more sources

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Medication reconciliation at patient admission: a randomized controlled trial

Pharmacy Practice, 2016
Objective: To measure length of hospital stay (LHS) in patients receiving medication reconciliation. Secondary characteristics included analysis of number of preadmission medications, medications prescribed at admission, number of discrepancies, and ...
Mendes AE, Lombardi NF, Andrzejevski VS, Frandoloso G, Correr CJ, Carvalho M   +5 more
doaj  

Physical activity to improve cognition in older adults: can physical activity programs enriched with cognitive challenges enhance the effects? A systematic review and meta-analysis [PDF]

, 2018
: EPHPP quality rating scores (DOCX 38 ...
A Damirchi, A Gutchess, A Lauenroth, A Schättin, AJ Hannan, AJ Saykin, AM Smith, Ann DeSmet, BE Ainsworth, C Cotman, C Fabre, C Legault, C Styliadis, C Voelcker-Rehage, CVL Teixeira, D Merom, D Sato, D Schoene, DE Barnes, E Stanmore, E van het Reve, F Li, Freja Gheysen, G Zheng, GA Panza, Greet Cardon, H van Praag, H Yokoyama, Ilse De Bourdeaudhuij, J León, J Nithianantharajah, J-C Kattenstroth, JH Ansai, JM Northey, K Fabel, K Kitazawa, K Knaepen, K Witte, KD Langdon, L Desjardins-Crepeau, L Hedges, LCW Lam, LLF Law, Louise Poppe, M Hagovska, M Hiyamizu, M-Y Siu, MA Fiatarone Singh, ME Hackney, ML Mustroph, MP Boisgontier, MW Voss, N Theill, P Dhami, P Eggenberger, P Eggenberger, P Fissler, P Jansen, P Maillot, P Müller, PA Reuter-Lorenz, PM Wayne, RC Petersen, RE Taylor-Piliae, S Colcombe, S Falbo, S Nishiguchi, S Norton, S Sungkarat, Sebastien Chastin, SH Kim, SJ Colcombe, Stephan Swinnen, T Shah, T Suzuki, TF Hughes, TJ Shors, WD Oswald, Wim Fias, World Health Organization, X Lu, X Zhu, Y Wang   +82 more
core   +7 more sources

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Investigator-initiated versus industry-sponsored trials – visibility and relevance of randomized controlled trials in clinical practice guidelines (IMPACT)

BMC Medical Research Methodology
Background The goal of evidence-based medicine is to make clinical decisions based on the best available, relevant evidence. For this to be possible, studies such as randomized controlled trials (RCTs), which are widely considered to provide the best ...
Manuel Hecht, Anette Blümle, Harald Binder, Martin Schumacher, Nadine Binder   +4 more
doaj   +1 more source

Topical Tazarotene Gel, 0.1%, as a Novel Treatment Approach for Atrophic Postacne Scars

JAMA Facial Plastic Surgery, 2019
Evidence is robust for the effectiveness of microneedle therapy in the management of postacne atrophic scarring. A home-based topical treatment with an efficacy comparable to microneedling would be a useful addition in the armamentarium of acne scar management.To compare the efficacy of topical tazarotene gel, 0.1%, with microneedling therapy in the ...
T P, Afra, Muhammed, Razmi T, Tarun, Narang, Sunil, Dogra, Ashok, Kumar   +4 more
openaire   +3 more sources

Hysteroscopy for treating subfertility associated with suspected major uterine cavity abnormalities [PDF]

, 2015
Background : Observational studies suggest higher pregnancy rates after the hysteroscopic removal of endometrial polyps, submucous fibroids, uterine septum or intrauterine adhesions, which are detectable in 10% to 15% of women seeking treatment for ...
Bosteels, Jan, Broekmans, Frank J, D'Hooghe, Thomas M, Kasius, Jenneke, Mol, Ben Willem J, Weyers, Steven   +5 more
core   +2 more sources

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

A realist process evaluation of Enhanced Triple P for Baby and Mellow Bumps, within a Trial of Healthy Relationship Initiatives for the Very Early years (THRIVE): study protocol for a randomized controlled trial [PDF]

, 2019
Background: THRIVE is a three-arm randomised controlled trial (RCT) that aims to evaluate whether antenatal and early postnatal interventions, Enhanced Triple B for Baby (ETPB) plus care as usual (CAU) or Mellow Bumps (MB) plus CAU (versus CAU alone ...
Buston, Katie, Henderson , Marion, McGee, Elizabeth, O'Brien, Rosaleen, White, Jane, Wight , Danny   +5 more
core   +4 more sources