Results 151 to 160 of about 188,812 (316)

Location‐Specific Hematoma Volume Predicts Early Neurological Deterioration in Supratentorial ICH

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Early neurological deterioration (END) adversely affects outcomes in patients with intracerebral hemorrhage (ICH). This study aimed to determine the location‐specific hematoma volumes for END in supratentorial ICH patients. Methods We retrospectively analyzed supratentorial ICH patients presenting from two prospective cohorts.
Zuoqiao Li, Guilin Meng, Zijie Wang, Xiao Hu, Jing Cheng, Chu Chen, Tiannan Yang, Jiaxin Luo, Zizhen Meng, Xueyun Liu, Qi Li   +10 more
wiley   +1 more source

Effectiveness of comprehensive geriatric assessment adapted to primary care when provided by a nurse or a general practitioner: the CEpiA cluster-randomised trial

BMC Medicine
Background The benefits of comprehensive geriatric assessment (CGA) are well established for hospital care but less so for primary care. Our primary objective was to assess the effect of two multifaceted interventions based on a CGA adapted for primary ...
Veronique Orcel, Leon Banh, Sylvie Bastuji-Garin, Vincent Renard, Emmanuelle Boutin, Amel Gouja, Philippe Caillet, Elena Paillaud, Etienne Audureau, Emilie Ferrat   +9 more
doaj   +1 more source

Efficacy and Safety of Inclisiran—An Assessment of the Consistency Between Randomized Controlled Trials and Real-World Evidence: A Systematic Review

Reviews in Cardiovascular Medicine
Background: This study aimed to compare the consistency in low-density lipoprotein cholesterol (LDL-C) reduction and the safety profile of the novel lipid-lowering agent inclisiran between randomized controlled trials (RCTs) and real ...
Yaru Lin, Haixiong Wang, Han Yang, Zekai Li   +3 more
doaj   +1 more source

Effectiveness of Acupotomy Combined with Topical Diclofenac for Knee Osteoarthritis: A Randomized Controlled Trial

Journal of Pain Research
We sought to determine whether acupotomy, when combined with topical diclofenac diethylamine emulgel, could (a) reduce pain, and (b) improve functional outcomes in patients with knee osteoarthritis, compared with topical diclofenac alone.This assessor-blinded, single-center randomized clinical trial was conducted at Beijing Hospital of Traditional ...
Kai Du, Wu-Zhong Cheng, Ao Li, Chen-Yu Zhang, Shi-Yan Yan, Fang Han, Ren Guo, Ping Chen, Wei-Shuai Du, Yong-Li Zuo, Qi-Heng Zuo, Shu-Ming Li   +11 more
openaire   +3 more sources

Paramagnetic Rim Lesions Are Associated With Trans‐Synaptic Degeneration of the Visual Pathway in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Retrograde trans‐synaptic degeneration (rTSD) from posterior visual pathway lesions in multiple sclerosis (MS) is characterized by hemi‐macular ganglion cell‐inner plexiform layer (GCIPL) thinning and contralateral visual field loss.
Abdul Jaber Tayem, Angel Liu, Sargis Manukyan, Mustafa Subhi, Elaina Luskin, Bryan Quah, Sreekanth Madhusoodhanan Nair, Arzu C. Has Silemek, Gabriela Zabala, Yujie Cui, Laura Locke, Paula Barreras, Marwa Kaisey, Vinicius Calsavara, Daniel S. Reich, Nancy L. Sicotte, Pascal Sati, Omar Al‐Louzi   +17 more
wiley   +1 more source

Cancer treatment pathways: AML a detailed costing study example [PDF]

, 2011
Background: AML is one of the most common and acute diseases among the types of leukaemia. The treatment costs for AML/APML are considerably high as it involves the use of expensive treatments (such as stem cell transplantation).
WANG, HAN-I
core  

Evaluating relapse prophylaxis in addition to interdisciplinary multimodal pain therapy for back pain: a randomised controlled trial

Journal of Rehabilitation Medicine
Objective: This study aimed to evaluate the effectiveness of a 12-month relapse prophylaxis following a 4-week interdisciplinary multimodal pain therapy approach for patients with back pain.
Julia Schmetsdorf, Kathrin Krüger, Jacqueline Posselt, Runde Werner, Hans-Georg Zechel, Thomas Kohlmann, Christian Krauth   +6 more
doaj   +1 more source

Quantifying the Impact of Ocrelizumab on Paramagnetic Rim Lesions in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Paramagnetic rim lesions (PRLs) are a subset of chronic active multiple sclerosis (MS) lesions marked by iron‐laden microglia and macrophages. Ocrelizumab, a monoclonal antibody targeting CD20+ B cells, suppresses acute MS activity, but its effect on PRLs remains unclear. In a longitudinal study of 29 ocrelizumab‐treated patients with at least
Kimberly H. Markowitz, Neha V. Safi, Iliana Pliska‐Bloch, Ulrike W. Kaunzner, Ha Luu, Mert Sisman, Yi Wang, Thanh D. Nguyen, Sandra Hurtado Rúa, Susan A. Gauthier   +9 more
wiley   +1 more source

Clinical Validation of Plasma p‐217tau in Neurological Diseases

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Plasma p‐217tau is a minimally invasive but specific biomarker for diagnosing Alzheimer's disease (AD). However, its disease specificity remains to be clinically evaluated. We validated the reliability of the p‐217tau biomarker in 12 other neurological diseases.
Takeshi Kawarabayashi, Takumi Nakamura, Ryoma Takahashi, Tetsuya Ueda, Seiji Kinoshita, Chikage Uchida, Takashi Sugawara, Kentaro Hashimoto, Kunihiko Ishizawa, Masakuni Amari, Hiroo Kasahara, Yoshio Ikeda, Masamitsu Takatama, Mikio Shoji   +13 more
wiley   +1 more source

Increasing response rates to lifestyle surveys: a review of methodology and 'good practice'.

Background Lifestyle surveys are traditionally used for collecting detailed population information about individual behaviours that impact on health.
Topping, Annie, McCluskey, Serena
core