Results 71 to 80 of about 346,597 (387)

Economic compensation interventions to increase uptake of voluntary medical male circumcision for HIV prevention: A systematic review and meta-analysis. [PDF]

, 2020
BackgroundEconomic compensation interventions may help support higher voluntary medical male circumcision (VMMC) coverage in priority sub-Saharan African countries.
Atkins, Kaitlyn, Baggaley, Rachel, Fonner, Virginia A, Kennedy, Caitlin E, O'Reilly, Kevin R, Rutherford, George W, Samuelson, Julia, Sweat, Michael D, Yeh, Ping Teresa   +8 more
core   +1 more source

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

Molecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath, Irene A. George, Srikanth S. Manda, Prasanth Ariyannur, Ekta R. Dhawale, Raja Sekhar Kommu, Rajan Datar, Darshana Patil, Vinita Trivedi, Manisha Singh, Kumar Prabhash, Sewanti Limaye, Richa Chauhan, Prashant Kumar   +13 more
wiley   +1 more source

Reporting of sex and gender in randomized controlled trials in Canada: a cross-sectional methods study

Research Integrity and Peer Review, 2017
Background Accurate reporting on sex and gender in health research is integral to ensuring that health interventions are safe and effective. In Canada and internationally, governments, research organizations, journal editors, and health agencies have ...
V. Welch, M. Doull, M. Yoganathan, J. Jull, M. Boscoe, S. E. Coen, Z. Marshall, J. Pardo Pardo, A. Pederson, J. Petkovic, L. Puil, L. Quinlan, B. Shea, T. Rader, V. Runnels, S. Tudiver   +15 more
doaj   +1 more source

Estimates of the mean difference in orthopaedic randomized trials: obligatory yet obscure

BMC Medical Research Methodology, 2021
Background Randomized controlled trials in orthopaedics are powered to mainly find large effect sizes. A possible discrepancy between the estimated and the real mean difference is a challenge for statistical inference based on p-values.
Lauri Raittio, Antti Launonen, Ville M. Mattila, Aleksi Reito   +3 more
doaj   +1 more source

Effectiveness of photodynamic therapy as an adjunct to topical antiviral therapy in the treatment of herpes labialis: A randomized controlled clinical trial

Photodiagnosis and Photodynamic Therapy, 2021
The present clinical trial assessed the effectiveness of photodynamic therapy in association with topical acyclovir in the treatment of herpes labialis in adolescent patients.45 individuals with herpes labialis were divided into three groups on the basis of provision of treatment.
openaire   +2 more sources

Probiotics for the Treatment of Atopic Dermatitis in Children: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

Frontiers in Cellular and Infection Microbiology, 2017
Objective: Atopic dermatitis (AD) is a prevalent, burdensome, and psychologically important pediatric concern. Probiotics have been suggested as a treatment for AD.
Ruixue Huang, Huacheng Ning, M. Shen, Jie Li, Jianglin Zhang, Xiang Chen   +5 more
semanticscholar   +1 more source

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

Molecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande, Marcela de Oliveira Silva, Mariana Bisarro dos Reis, Rodrigo de Oliveira Cavagna, Luciane Sussuchi, Icaro Alves Pinto, Natalia Zampieri Pontes, Rodrigo Sampaio Chiarantano, Flavio Augusto Ferreira da Silva, Pedro de Marchi, Letícia Ferro Leal, Rui M. Reis   +11 more
wiley   +1 more source

COMPARISON OF PHARMACOLOGY AGENTS EFFECT IN TREATING URETERAL STENT RELATED SYMPTOMS: SYSTEMATIC REVIEW & META-ANALYSIS OF RANDOMIZED CONTROLLED TRIAL¬

Jurnal Urologi Indonesia
Objective: We wish to update existing meta-analyses to assess the effectiveness of pharmacological agents against ureteral stent-related symptoms with better design of RCTs, as well as more valid and reliable measurement methods.
Andi As'ad Mubarak, Muhammad Ainul Mahfuz, Abdul Aziz, Muhammad Sopiyudin Dahlan   +3 more
doaj   +1 more source

A randomized control trial assessing the effect of a pharmaceutical care service on Syrian refugees’ quality of life and anxiety

Pharmacy Practice, 2020
Background: Syrian refugees residing in Jordan suffer from chronic illnesses, low quality of life (QoL) and anxiety. Pharmacists delivering the medication review service can have a role in improving this growing worldwide problem.
Majdoleen Al alawneh , Nabeel Nuaimi , Eman Abu-Gharbieh , Iman A. Basheti   +3 more
doaj   +1 more source

Study-based registers of randomized controlled trials: Starting a systematic review with data extraction or meta-analysis [PDF]

BioImpacts, 2017
Introduction: Despite years of use of study-based registers for storing reports of randomized controlled trials (RCTs), the methodology used in developing such registers/databases has not been documented.
Farhad Shokraneh, Clive Elliott Adams
doaj   +1 more source