Results 81 to 90 of about 1,792,348 (283)
Oral versus topical tamoxifen in cyclical mastalgia—A randomized controlled trial
The Breast Journal, 2019 Mastalgia affects premenopausal in which cyclical mastalgia affects up to 40% of women. In approximately 8% of these women, pain will be severe and interfere with their normal activities. oral tamoxifen widely used in the treatment of mastalgia is associated with a wide range of side effects. Topical tamoxifen has the potential to be a more efficacious
Divya Dhananjay Singh +3 more
openaire +2 more sources
Estimates of the mean difference in orthopaedic randomized trials: obligatory yet obscure
BMC Medical Research Methodology, 2021 Background Randomized controlled trials in orthopaedics are powered to mainly find large effect sizes. A possible discrepancy between the estimated and the real mean difference is a challenge for statistical inference based on p-values.
Lauri Raittio +3 more
doaj +1 more source
Citation classics in systematic reviews and meta-analyses : who wrote the top 100 most cited articles? [PDF]
, 2013 Background: Systematic reviews of the literature occupy the highest position in currently proposed hierarchies of evidence. The aims of this study were to assess whether citation classics exist in published systematic review and meta-analysis (SRM ...
Clarke, Aileen +4 more
core +4 more sources
Pharmacy Practice, 2020 Background: Syrian refugees residing in Jordan suffer from chronic illnesses, low quality of life (QoL) and anxiety. Pharmacists delivering the medication review service can have a role in improving this growing worldwide problem.
Majdoleen Al alawneh +3 more
doaj +1 more source
A matching design for augmenting a randomized clinical trial with external control [PDF]
arXiv, 2022 The use of information from real world to assess the effectiveness of medical products is becoming increasingly popular and more acceptable by regulatory agencies. According to a strategic real-world evidence framework published by U.S. Food and Drug Administration, a hybrid randomized controlled trial that augments internal control arm with real-world
arxiv
Non-Inferiority Trials in Surgical Oncology [PDF]
, 2018 The classical randomized controlled clinical trial is designed to prove superiority of an investigational therapy over an established therapy or placebo (here referred to as "superiority trial”).
Adamina, Michel +2 more
core
BMC Anesthesiology, 2018 BackgroundThe safety and efficiency of intravenous administration of tranexamic acid (TXA) in coronary artery bypass grafting (CABG) remains unconfirmed.
Yanting Zhang +6 more
semanticscholar +1 more source
Efficacy and safety of 0.5% colchicine cream versus 5% 5-fluorouracil cream in the treatment of cutaneous field cancerization: a randomized clinical trial [PDF]
Anais Brasileiros de DermatologiaBackground 5-Fluorouracil (5-FU) is a first-line drug to treat cutaneous field cancerization (CFC). There are few clinical trials with topical colchicine (COL).
Amanda Soares Teixeira +3 more
doaj +1 more source
Are Soy-based Proteins, Meals, and Diets an Effective Treatment in Reducing Waist Circumference in Overweight and Obese Adults Ages 20-75 Years? [PDF]
, 2017 Objective: The objective of this evidence based medicine review is to determine whether or not soy-based proteins, meals, and diets are effective treatments in reducing waist circumference in overweight and obese adults ages 20-75 years.
Lin, Lisa
core +1 more source
Frontiers in Cellular and Infection Microbiology, 2017 Objective: Atopic dermatitis (AD) is a prevalent, burdensome, and psychologically important pediatric concern. Probiotics have been suggested as a treatment for AD.
Ruixue Huang +5 more
semanticscholar +1 more source