Results 81 to 90 of about 337,732 (285)

Drugs for preventing red blood cell dehydration in people with sickle cell disease. [PDF]

, 2016
BACKGROUND: Sickle cell disease is an inherited disorder of hemoglobin, resulting in abnormal red blood cells. These are rigid and may block blood vessels leading to acute painful crises and other complications.
Ballas, Samir K., Nagalla, Srikanth
core   +2 more sources

OnabotulinumtoxinA for neurogenic detrusor overactivity and dose differences: a systematic review

International Brazilian Journal of Urology, 2015
Purpose To evaluate the efficacy and safety of onabotulinumtoxinA for patients with neurogenic detrusor overactivity (NDO). Materials and Methods We searched the Cochrane Library, PUBMED, EMBASE, Chinese Bio-medicine database, China Journal Full-text ...
Rui Zhang, Yongteng Xu, Shengping Yang, Hui Liang, Yunxin Zhang, Yali Liu   +5 more
doaj   +1 more source

Implementation of a nurse-led self-management support intervention for patients with cancer-related pain: a cluster randomized phase-IV study with a stepped wedge design (EvANtiPain)

BMC Cancer, 2020
Background Pain self-management support interventions were effective in controlled clinical trials and meta analyses. However, implementation of these complex interventions may not translate into identical effects. This paper evaluates the implementation
Silvia Raphaelis, Florian Frommlet, Hanna Mayer, Antje Koller   +3 more
doaj   +1 more source

Randomized controlled trials in ophthalmology: a bibliometric study

F1000Research, 2019
Background: Randomized controlled trials (RCTs) are situated at the top of hierarchy of evidence-based medicine, where its number and quality are important in the assessment of quality of evidence in a medical field.
S. AlRyalat, Areen Abukahel, K. Elubous
semanticscholar   +1 more source

Cluster randomised trials in the medical literature: two bibliometric surveys [PDF]

, 2004
Background: Several reviews of published cluster randomised trials have reported that about half did not take clustering into account in the analysis, which was thus incorrect and potentially misleading.
A Donner, A Donner, A Donner, C Emslie, CM Wright, CR Elley, D Nutbeam, DG Altman, DG Altman, DM Murray, E Rink, G Meyer, J Cornfield, J Martin Bland, JCFM Wetsteyn, JM Bland, JM Bland, JM Simpson, MAH Russell, MJ Gardner, MJ Gardner, MK Campbell, P Isaakidis, S Puffer, SM Eldridge, SM Kerry, SM Kerry, SM Kerry, SP Varnell   +28 more
core   +4 more sources

The effects of chronic and acute physical activity on working memory performance in healthy participants: a systematic review with meta-analysis of randomized controlled trials

Systematic Reviews, 2017
BackgroundUnderstanding how physical activity (PA) influences cognitive function in populations with cognitive impairments, such as dementia, is an increasingly studied topic yielding numerous published systematic reviews.
Azeem Rathore, B. Lom
semanticscholar   +1 more source

Challenges in evaluating surgical innovation [PDF]

, 2009
Research on surgical interventions is associated with several methodological and practical challenges of which few, if any, apply only to surgery. However, surgical evaluation is especially demanding because many of these challenges coincide.
Blazeby, Jane M, Boutron, Isabelle, Clavein, Pierre-Alain, Cook, Jonathan Alistair, Ergina, Patrick L, Reeves, Barnaby C, Seiler, Christoph M   +6 more
core   +1 more source

Continuous feeding versus intermittent bolus feeding for premature infants with low birth weight: a meta-analysis of randomized controlled trials

European Journal of Clinical Nutrition, 2019
Background/objectives Clinical risks and advantages of both continuous feeding and intermittent feeding for preterm infants have been presented in previous studies.
Yan Wang, Wei Zhu, Bi-ru Luo
semanticscholar   +1 more source

Maternal Obesity and Fetal Macrosomia: An Integrative Review of the Literature Regarding Interventions [PDF]

, 2018
Research suggests pre-pregnancy obesity is associated with an increased risk of macrosomia in the newborn. Since women are expected to gain weight during pregnancy, the standard recommendation of weight loss for obesity is not ideal for this population ...
Stalcup, Charity
core   +1 more source

Patient level pooled analysis of 68,500 patients from seven major vitamin D fracture trials in the US and Europe [PDF]

, 2010
Objectives To identify participants’ characteristics that influence the anti-fracture efficacy of vitamin D or vitamin D plus calcium with respect to any fracture, hip fracture, and clinical vertebral fracture and to assess the influence of dosing ...
Abrahamsen, B, Anderson, F, Avenell, A, Brixen, K, Cooper, C, F, Hutchison, Francis, R M, Jackson, R, Johansen, A, LaCroix, A Z, Masud, T, Meyer, H E, Mosekilde, L, Rejnmark, L, Robbins, J A, Smith, H, The DIPART (vitamin D Individual Patient Analysis of Randomized Trials) Group, Torgerson, D, Wactawski-Wende, J   +18 more
core   +2 more sources