Long-term efficacy and safety of first-line ibrutinib treatment for patients with CLL/SLL: 5 years of follow-up from the phase 3 RESONATE-2 study. [PDF]
RESONATE-2 is a phase 3 study of first-line ibrutinib versus chlorambucil in chronic lymphocytic leukemia (CLL)/small lymphocytic lymphoma (SLL). Patients aged ≥65 years (n = 269) were randomized 1:1 to once-daily ibrutinib 420 mg continuously or ...
Bairey, Osnat +19 more
core +3 more sources
ABSTRACT Introduction Cognitive impairment and exercise intolerance are common in dialysis patients. Cerebral perfusion and oxygenation play a major role in both cognitive function and exercise execution; HD session per se aggravates cerebral ischemia in this population. This study aimed to compare cerebral oxygenation and perfusion at rest and in mild
Marieta P. Theodorakopoulou +10 more
wiley +1 more source
The present work sheds light on the estimation procedure of mean number of per- sons bearing a rare sensitive characteristic utilizing Poisson distribution.
G N Singh, Surbhi Suman
doaj
Altruistic donation to improve survey responses: a global randomized trial
Objective Web-based platforms have revolutionized the ability for researchers to perform global survey research. Methods to incentivize participation have been singularly focused on European and North American participants with varied results.
Andrew J. Cohen +8 more
doaj +1 more source
Computerized Response Inhibition Training For Children With Trichotillomania [PDF]
Evidence suggests that trichotillomania is characterized by impairment in response inhibition, which is the ability to suppress pre-potent/dominant but inappropriate responses. This study sought to test the feasibility of computerized response inhibition
Bauer, Christopher C. +4 more
core +2 more sources
Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM
Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley +1 more source
A Practically Competitive and Provably Consistent Algorithm for Uplift Modeling
Randomized experiments have been critical tools of decision making for decades. However, subjects can show significant heterogeneity in response to treatments in many important applications.
Fang, Xiao +2 more
core +1 more source
An effective modeling framework for the analysis of interconnects subject to line-edge roughness [PDF]
This letter proposes a complete and efficient simulation framework to assess the effects of line-edge roughness appearing in on-chip lines. The modeling approach consists of three steps.
De Zutter, Daniël +2 more
core +1 more source
Mapping the evolution of mitochondrial complex I through structural variation
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin +2 more
wiley +1 more source
Evaluating rule breaking behavior in a Nigerian protected forest reserve area
This paper investigated the rule breaking conduct in a Nigerian protected forest reserve area in order to exploit natural resources using Randomized Response Technique (RRT) for data collection.
O.A. Akinsorotan +3 more
doaj +1 more source

