Results 81 to 90 of about 1,011,036 (303)

Improved Randomized Response Techniques

, 2014
One way to protect an interviewee’s privacy when responding to a sensitive questions is through the use of a method called Randomized Response Technique (RRT).
Johnson, Michael Lee
core  

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

Randomized Conditional Response [PDF]

, 1975
This issue was undated. The date given is an estimate.4 pages, 1 article*Randomized Conditional Response* (DeLacy, Peter W.) 4 ...
DeLacy, Peter W., Cornell University. Dept. of Biological Statistics and Computational Biology., Cornell University. Biometrics Unit., Cornell University. Dept. of Biometrics.   +3 more
core  

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

A Review on Indirect Answering Techniques to Sensitive Binomial Questions

مجله اپیدمیولوژی ایران, 2014
Sensitive questions about people’s behaviors are often discussed in studies in the fields of human, social, and medical sciences. Obtaining valid answers to these kinds of questions is one of the main challenges in the mentioned studies.
M Banayejeddi, S Navadeh, A Fotouhi, K Yazdani   +3 more
doaj  

Selective Trials: A Principal-Agent Approach to Randomized Controlled Experiments [PDF]

We study the design of randomized controlled experiments in environments where outcomes are significantly affected by unobserved effort decisions taken by the subjects(agents). While standard randomized controlled trials (RCTs) are internally consistent,
Erik Snowberg, Gerard Padro i Miquel, Sylvain Chassang   +2 more
core  

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Novel estimation methods using randomized response sampling

, 2019
In this thesis, I introduced a new problem of simultaneous estimation of means of two quantitative sensitive variables by using only one randomized response and another pseudo response from a respondent in a sample.
Ahmed, Segun Moses
core  

Early intervention during imatinib therapy in patients with newly diagnosed chronic-phase chronic myeloid leukemia: a study of the Spanish PETHEMA group

Haematologica, 2010
Background Despite the favorable results of imatinib front line in chronic-phase chronic myeloid leukemia there is room for improvement.Design and Methods Early intervention during imatinib therapy was undertaken in 210 adults with chronic-phase chronic ...
Francisco Cervantes, Pilar López-Garrido, María-Isabel Montero, Fermín Jonte, Jesús Martínez, Juan-Carlos Hernández-Boluda, María Calbacho, Anna Sureda, Gloria Pérez-Rus, José B. Nieto, Cristina Pérez-López, José Román-Gómez, Marcos González, Arturo Pereira, Dolors Colomer   +14 more
doaj   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source