Results 71 to 80 of about 8,348,711 (246)
Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis
FEBS Letters, EarlyView.This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng +8 more
wiley +1 more source
Modified randomized response technique to detect respondent reticence
Journal of the College of Community Physicians, 2017 No abstract ...
Dulani Samaranayake
doaj +1 more source
Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy
FEBS Letters, EarlyView.The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley +1 more source
FEBS Letters, EarlyView.Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana +3 more
wiley +1 more source
A Review on Indirect Answering Techniques to Sensitive Binomial Questions
مجله اپیدمیولوژی ایران, 2014 Sensitive questions about people’s behaviors are often discussed in studies in the fields of human, social, and medical sciences. Obtaining valid answers to these kinds of questions is one of the main challenges in the mentioned studies.
M Banayejeddi +3 more
doaj
FEBS Letters, EarlyView.Which brain hemisphere controls writing? This review synthesizes all five functional transcranial Doppler studies of writing (handwriting and typing) published to date in adults and children. Right‐handers show left‐hemispheric dominance for the linguistic component of writing (written word generation), whereas findings for left‐handers remain ...
Marietta Papadatou‐Pastou
wiley +1 more source
A stratified unrelated question randomized response model
Randomized response, Stratified random sampling, Sensitive characteristics, Dichotomous population, Estimation of proportion,
Matthew Elam, Jong-Min Kim
core +1 more source
Do ACE inhibitors improve the response to exercise training in functionally impaired older adults? A randomized controlled trial [PDF]
, 2014 <br>Background: Loss of muscle mass and strength with ageing is a major cause for falls, disability, and morbidity in older people. Previous studies have found that angiotensin-converting enzyme inhibitors (ACEi) may improve physical function in ...
Sumukadas, Deepa +8 more
core +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Improved Randomized Response Techniques
, 2014 One way to protect an interviewee’s privacy when responding to a sensitive questions is through the use of a method called Randomized Response Technique (RRT).
Johnson, Michael Lee
core +1 more source