Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
On the Efficiency of the Newly Developed Composite Randomized Response Technique
Computational and Mathematical MethodsIn today’s data-driven decision-making era, acquiring accurate information is vital. However, survey research faces challenges with sensitive issues. To address this, the Composite Randomized Response Technique (CRRT) was introduced in estimating the ...
Senani P. Dlamini +2 more
doaj +1 more source
Comment on "Recreational Athletes' Use of Performance‑Enhancing Substances: Results from the First European Randomized Response Technique Survey". [PDF]
Sports Med Open, 2023 Petrou M, Lazuras L.
europepmc +1 more source
Heikle Fragen in mündlichen Interviews: Ergebnisse einer Methodenstudie im studentischen Milieu (Sensitive Questions in Face-to-Face Interviews: Findings of a Methodological Study with University Students) [PDF]
In einem "sensitive topic survey" mit Studierenden der Universität Mainz (n=578) wurde die Brauchbarkeit von drei Techniken zur Erhebung heikler Sachverhalte untersucht: Wording/Framing-Techniken, die Technik des vertraulichen Kuverts und die Randomized ...
Peter Preisendörfer
core
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Molecular Oncology, EarlyView.Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
Authors' Reply to Petrou & Lazuras: 'Recreational Athletes' Use of Performance-Enhancing Substances: Results from the First European Randomized Response Technique Survey'. [PDF]
Sports Med Open, 2023 Christiansen AV +3 more
europepmc +1 more source
Implementing optimal control pulse shaping for improved single-qubit gates
, 2010 We employ pulse shaping to abate single-qubit gate errors arising from the weak anharmonicity of transmon superconducting qubits. By applying shaped pulses to both quadratures of rotation, a phase error induced by the presence of higher levels is ...
Chow, J. M. +6 more
core +1 more source
Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics
FEBS Open Bio, EarlyView.Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini +2 more
wiley +1 more source
FEBS Open Bio, EarlyView.Chemotherapies such as doxorubicin can have toxic effects on healthy cardiovascular/heart tissue. Following up on a doxorubicin toxicity study in mice without tumors where nitrate water was cardioprotective (lessened toxicity), this study with tumor‐bearing mice undergoing doxorubicin treatment showed no negative effect of nitrate and nitrite on drug ...
Rama D. Yammani +7 more
wiley +1 more source
Estimation of the Proportion of Potential Nondisclosed Men Who Have Sex With Men Among Self-Reported Heterosexual Men With HIV Using a Randomized Response Technique. [PDF]
Sex Transm Dis, 2022 Chen Y +8 more
europepmc +1 more source