Results 71 to 80 of about 2,080,251 (318)

An initial investigation of neural changes in overweight adults with food cravings after emotional freedom techniques [PDF]

open access: yes, 2019
Background: This pilot randomised clinical trial investigated the effect of Clinical Emotional Freedom Techniques (EFT) on brain activation in response to food craving stimuli using functional magnetic resonance imaging.
Buchan, Craig   +5 more
core   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

Optimal strategy for improved estimation of population mean of sensitive variable using non-sensitive auxiliary variable

open access: yesJournal of Big Data
To improve the transformed ratio type estimators, this study uses new population parameters that are derived from extra information using a randomized response technique (RRT).
Abdullah A. Zaagan   +6 more
doaj   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

A novel efficient randomized response model designed for attributes of utmost sensitivity

open access: yesHeliyon
The existence of potential incomplete truthful reporting emerges when dealing with topics of great sensitivity. This paper introduces a novel, efficient randomized response model to address the challenges of untruthful reporting.
Ahmad M. Aboalkhair   +4 more
doaj   +1 more source

Targeted genome-wide enrichment of functional regions.

open access: yesPLoS ONE, 2010
Only a small fraction of large genomes such as that of the human contains the functional regions such as the exons, promoters, and polyA sites. A platform technique for selective enrichment of functional genomic regions will enable several next ...
Periannan Senapathy   +4 more
doaj   +1 more source

Filtered Randomized Response Technique

open access: yesCommunications for Statistical Applications and Methods, 2006
Randomized response technique is a survey technique for eliminating evasive answer bias. This technique is popular in social survey for sensitive issues. In this paper we present a simple and obvious procedure for estimating the population proportion of a sensitive group. Here, we shows the weak point in the method of Kim and Warde (2005).
openaire   +2 more sources

Privacy via the Johnson-Lindenstrauss Transform

open access: yes, 2012
Suppose that party A collects private information about its users, where each user's data is represented as a bit vector. Suppose that party B has a proprietary data mining algorithm that requires estimating the distance between users, such as clustering
Kenthapadi, Krishnaram   +3 more
core   +3 more sources

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