Results 31 to 40 of about 258,588 (291)

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Constructing indirect randomized response techniques using symmetry of response

, 2009
This paper considers the problem of estimating the population proportion when the study variable is sensitive in nature. Some indirect randomized response techniques are proposed, which maintain the requirement of efficiency and protection of ...
張紘炬; Chang, Horng-jinh; Huang, Kuo-chung, Wu, Chao-hsien
core   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Asking sensitive questions: Possibilities and limits of randomized response and other techniques in different survey modes [PDF]

, 2013
In our project within the DFG Priority Programme on Survey Methodology (SPP 1292) we conducted various methodological studies on survey techniques for asking sensitive questions.
Krumpal, Ivar, Wolter, Felix, Höglinger, Marc, Jann, Ben   +3 more
core  

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

A Survey on Illicit Drug Use among University Students by Binary Randomized Response Technique: Crosswise Design

Sakarya Üniversitesi Fen Bilimleri Enstitüsü Dergisi, 2020
This paper aims to introduce Randomized Response Techniques (RRT’s) and show that how RRT’s are implemented in surveys in which sensitive behaviors are investigated.
Nilgün Özgül
doaj   +1 more source

Indirect questioning methods for sensitive survey questions: Modelling criminal behaviours among a prison population.

PLoS ONE, 2021
Information such as the prevalence and frequency of criminal behaviour is difficult to estimate using standard survey techniques because of the tendency of respondents to withhold or misrepresent information.
Beatriz Cobo, Eva Castillo, Francisca López-Torrecillas, María Del Mar Rueda   +3 more
doaj   +1 more source

More is not always better: An experimental individual-level validation of the randomized response technique and the crosswise model. [PDF]

PLoS ONE, 2018
Social desirability and the fear of sanctions can deter survey respondents from responding truthfully to sensitive questions. Self-reports on norm breaking behavior such as shoplifting, non-voting, or tax evasion may thus be subject to considerable ...
Marc Höglinger, Ben Jann
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source