Results 41 to 50 of about 11,790,111 (286)
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Improved Randomized Response Techniques
, 2014 One way to protect an interviewee’s privacy when responding to a sensitive questions is through the use of a method called Randomized Response Technique (RRT).
Johnson, Michael Lee
core +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Randomized Response Techniques for Complex Survey Designs [PDF]
Statistical Papers, 2007 Singh et al. ([13]) pointed out that the Randomized response (RR) technique proposed by Moors ([9]) is not desirable because it fails to protect the confidentiality of the respondents and they provided two alternative strategies free from the above drawback but limited to SRSWOR sampling only.
openaire +1 more source
Estimation of Small Area Total with Randomized Data
Revstat Statistical Journal, 2020 In social surveys involving questions that are sensitive or personal in nature, respondents may not provide correct answers to certain questions asked by the interviewer.
Shakeel Ahmed +3 more
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
How privacy may be protected in optional randomized response surveys [PDF]
, 2020 There are materials in literature about how privacy on stigmatizing features like alcoholism, history of tax-evasion, or testing positive in AIDS-related testing may be partially protected by a proper application of randomized response techniques (RRT ...
Pal, Sanghamitra +2 more
core +2 more sources
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Journal für Kulturpflanzen, 2022 This study aims to determine the response of the yield and fresh stover weight of corn under mass selection by pollination control and base index techniques and to determine the increase in yield and fresh stover after seven mass selection cycles ...
I Wayan Sudika, I Nyoman Soemeinaboedhy
doaj +1 more source
Artificial molecular machines and motors—Design and control of nanoscale motion
FEBS Letters, EarlyView.Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley +1 more source