Results 91 to 100 of about 164,582 (257)

Parallelisation for data-intensive applications over peer-to-peer networks [PDF]

In Data Intensive Computing, properties of the data that are the input for an application decide running performance in most cases. Those properties include the size of the data, the relationships inside data, and so forth.
Chen, Xinuo
core  

Energy-efficient and privacy-preserving spatial range aggregation query processing in wireless sensor networks

International Journal of Distributed Sensor Networks, 2019
The existing privacy-preserving aggregation query processing methods in sensor networks rely on pre-established network topology and require all nodes in the network to participate in query processing.
Liang Liu, Zhenhai Hu, Lisong Wang
doaj   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

A Line Graph-Based Continuous Range Query Method for Moving Objects in Networks

ISPRS International Journal of Geo-Information, 2016
The rapid growth of location-based services has motivated the development of continuous range queries in networks. Existing query algorithms usually adopt an expansion tree to reuse the previous query results to get better efficiency.
Hengcai Zhang, Feng Lu, Jie Chen
doaj   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Efficient dynamic range minimum query

, 2016
The Range Minimum Query problem consists in answering efficiently the simple question: “what is the minimal element between two specified indices of a given array?”.
Léonard, Martine, Salson, Mikael, Heliou, A., Mouchard, L., Héliou, Alice, Léonard, M., Salson, M., Mouchard, Laurent   +7 more
core   +1 more source

PixelQuery: Efficient Distance Range Join Query Technique for Visualization Analysis

ISPRS International Journal of Geo-Information
A distance range join query (DRJQ) is a fundamental and critical operation in spatial database queries. It identifies geographic elements within specified distance ranges.
Bo Pang, Zebang Liu, Wei Xiong, Mengyu Ma   +3 more
doaj   +1 more source

Direction-Aware Nearest Neighbor Query

IEEE Access, 2019
Although the direction aspect is as important as the distance aspect when retrieving spatial objects, the studies of direction-aware queries are limited. The direction-based surrounder query cannot guarantee good directional diversity.
Xi Guo, Xiaochun Yang
doaj   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source