Results 71 to 80 of about 164,582 (257)

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Continuous Nearest Neighbor Queries over Sliding Windows [PDF]

open access: yes, 2007
—This paper studies continuous monitoring of nearest neighbor (NN) queries over sliding window streams. According to this model, data points continuously stream in the system, and they are considered valid only while they belong to a sliding window that ...
Papadias, Dimitris   +3 more
core   +1 more source

New construction of secure range query on encrypted data in cloud computing

open access: yesTongxin xuebao, 2015
To solve the information leakage problem resulting from several assertions of previous range query solutions,there is a secure range query scheme with one assertion (SRQSAE scheme),and the scheme is claimed to be secure against ciphertext-only attack.The
Shao-hui WANG   +3 more
doaj   +2 more sources

Mixed‐class J‐domain protein scaffolds promote expanded aggregate handling and multivalent Hsp70 engagement during functional disaggregase assembly

open access: yesFEBS Letters, EarlyView.
Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley   +1 more source

A distributed range query framework for the internet of things

open access: yes, 2015
The range query referring to the Internet of Things is a tough challenge since the data information is fully distributed. In order to support efficient range query, most existing approaches focused on designing the data management mechanism, which ...
Tingting Zhang   +5 more
core   +1 more source

Secure and Efficient Cluster-Based Range Query Processing in Wireless Sensor Networks

open access: yesJournal of Electrical and Computer Engineering, 2018
In wireless sensor networks, preserving privacy is more important and has attracted more attentions. Protecting data and sensor privacy while collecting and computing query results is a challenge.
Liming Zhou, Yingzi Shan, Lu Chen
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

A survey on the use of relevance feedback for information access systems

open access: yes, 2003
Users of online search engines often find it difficult to express their need for information in the form of a query. However, if the user can identify examples of the kind of documents they require then they can employ a technique known as relevance ...
Ruthven, Ian, Lalmas, Mounia
core   +1 more source

A Range Query Scheme for Spatial Data with Shuffled Differential Privacy

open access: yesMathematics
The existing high-dimensional or multi-dimensional geographic spatial datasets have a large amount of data. When third-party servers collect and publish them, privacy protection is required to prevent sensitive information from being leaked.
Kaixuan Li   +3 more
doaj   +1 more source

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