Results 61 to 70 of about 164,582 (257)
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Adaptive Range Counting and Other Frequency-Based Range Query Problems [PDF]
, 2012 I hereby declare that I am the sole author of this thesis. This is a true copy of the thesis, including any required final revisions, as accepted by my examiners. I understand that my thesis may be made electronically available to the public.
Wilkinson, Bryan T., Bryan T. Wilkinson
core
Moving range query processing in spatial databases
, 2017 Recent developments in mobile communications have brought dramatic and fundamental changes to the modern world. These developments have resulted in a great demand for applications that integrate geographic locations and services to fulfill the user’s ...
AL-Khalidi, Haidar (3774052)
core +1 more source
α‐Synuclein aggregation landscape from phase separation to neurotoxic intermediates
FEBS Letters, EarlyView.Alpha‐synuclein aggregation in Parkinson's disease involves a complex landscape of transient intermediates, including oligomers, fibrils and liquid–liquid phase separation (LLPS). A view is emerging in which LLPS maturation into solid‐like condensates may contribute to the formation of neurotoxic species.
Silvia Arino +2 more
wiley +1 more source
ORange: Objective-Aware Range Query Refinement
, 2014 In this demo paper we present Orange, a system prototype for objective-aware range query refinement. Orange essentially refines a range query to meet a pre-specified cardinality constraint while taking into account the (dis)similarity between the initial
Shazia Sadiq +11 more
core +1 more source
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
An Efficient Text Interval Hot Word Query Algorithm [PDF]
Jisuanji gongcheng, 2018 Text interval hot word query is based on user-specified query time range,it extracts from the text data hot words.Existing hot words extraction algorithm is generally oriented to mining tasks,which has a high time complexity and is difficult to be ...
ZHAO Zhizhou,LU Chang,HE Zhenying,WANG Xiaoyang
doaj
Monitoring Moving Queries inside a Safe Region
The Scientific World Journal, 2014 With mobile moving range queries, there is a need to recalculate the relevant surrounding objects of interest whenever the query moves. Therefore, monitoring the moving query is very costly.
Haidar Al-Khalidi +3 more
doaj +1 more source