Results 121 to 130 of about 1,113,430 (306)

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

FEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara, Kinga Skoczek, Elzbieta Pyza, Milena Damulewicz   +3 more
wiley   +1 more source

Analysis of Breast Cancer Data using Kaplan–Meier Survival Analysis

Journal of Kufa for Mathematics and Computer, 2012
The Kaplan–Meier estimator is a very popular that provides better estimates to determine the median when the sample size is reasonably large.
Nazera Khalil Dakhil, Yahya Mahdi Al–mayali, Muna Abbas Al–A'bidy   +2 more
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

A novel index of functional connectivity: phase lag based on Wilcoxon signed rank test. [PDF]

Cogn Neurodyn, 2021
Li X, Wu Y, Wei M, Guo Y, Yu Z, Wang H, Li Z, Fan H.   +7 more
europepmc   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

A Privacy-Preserving Log-Rank Test for the Kaplan-Meier Estimator With Secure Multiparty Computation: Algorithm Development and Validation. [PDF]

JMIR Med Inform, 2021
von Maltitz M, Ballhausen H, Kaul D, Fleischmann DF, Niyazi M, Belka C, Carle G.   +6 more
europepmc   +1 more source

A unifying theory of tests of rank [PDF]

Journal of Econometrics, 2017
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire   +3 more sources

Monte Carlo methods for variance reduction and log-rank test

, 2022
Monte Carlo methods are frequently used in Bayesian analysis to use randomness to solve problems. This work consists of two parts concerning two fundamental areas of statistics, estimation and hypothesis testing.
张焱, Zhang, Yan
core  

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

A Socioecological Assessment of Vulture Abundance and Community Perceptions Before and After Landfill Site Shift in Pokhara, Nepal

Ecology and Evolution
South Asia is home to nine species of vultures, and Nepal hosts all of them. Remarkably, all these species have also been recorded in Pokhara. This could be attributed to Pokhara's location along bird migration pathways and the year‐round availability of
Binita Timilsina, Mohan Bucha Magar, Sangam Poudel, Dinesh Bhusal, Dipa Gurung, Ankit Bilash Joshi, Yajna Prasad Timilsina   +6 more
doaj   +1 more source