Results 111 to 120 of about 3,905,246 (313)

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Asymptotic Power Functions of Some Statistical Rank Order Tests [PDF]

open access: yesThe Egyptian Statistical Journal, 1957
S.R. Salib
doaj   +1 more source

An Exact Paired Rank Test

open access: yesBiometrical Journal, 2002
An exact rank test for two dependent samples based on overall mid-ranks is discussed which can be applied to metric as well as to ordinal data. The exact conditional distribution of the test statistic given the observed vector of rank differences is determined. A recursion formula is given as well as a fast shift algorithm in SAS/IML code. Moreover, it
Munzel, U., Brunner, E.
openaire   +2 more sources

PSYNDEX Tests Review für KT - KRAMER-TEST

open access: yes, 1982
This is a PSYNDEX Tests Review of KT - KRAMER-TEST. PSYNDEX Tests Reviews are written in German and describe and evaluate psychological and educational tests used in the German-speaking countries.
Kramer, Josefine
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Modeling Multivariate Distributions with Continuous Margins Using the copula R Package

open access: yesJournal of Statistical Software, 2010
The copula-based modeling of multivariate distributions with continuous margins is presented as a succession of rank-based tests: a multivariate test of randomness followed by a test of mutual independence and a series of goodness-of-fit tests.
Ivan Kojadinovic, Jun Yan
doaj  

A Jackknife Correction to a Test for Cointegration Rank

open access: yesEconometrics, 2015
This paper investigates the performance of a jackknife correction to a test for cointegration rank in a vector autoregressive system. The limiting distributions of the jackknife-corrected statistics are derived and the critical values of these ...
Marcus J. Chambers
doaj   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

The Brier score does not evaluate the clinical utility of diagnostic tests or prediction models

open access: yesDiagnostic and Prognostic Research, 2017
Background A variety of statistics have been proposed as tools to help investigators assess the value of diagnostic tests or prediction models. The Brier score has been recommended on the grounds that it is a proper scoring rule that is affected by both ...
Melissa Assel   +2 more
doaj   +1 more source

On rank estimation in semidefinite matrices [PDF]

open access: yes
This work concerns the problem of rank estimation in semidefinite matrices, having either indefinite or semidefinite matrix estimator satisfying a typical asymptotic normality condition.
Stephen G. Donald   +2 more
core  

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