Results 111 to 120 of about 16,829,601 (344)

Accurate and efficient P-values for rank-based independence tests with clustered data using a saddlepoint approximation

open access: yesScientific Reports
Accurate statistical inference for clustered data—common in multi-center clinical trials and longitudinal studies—poses significant challenges due to within-cluster correlation. Rank-based tests like the logrank, Wilcoxon, and Datta-Satten are valued for
Haidy A. Newer
doaj   +1 more source

An Exact Paired Rank Test

open access: yesBiometrical Journal, 2002
An exact rank test for two dependent samples based on overall mid-ranks is discussed which can be applied to metric as well as to ordinal data. The exact conditional distribution of the test statistic given the observed vector of rank differences is determined. A recursion formula is given as well as a fast shift algorithm in SAS/IML code. Moreover, it
Munzel, U., Brunner, E.
openaire   +2 more sources

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Determining the number of cointegrating relations under rank constraints [PDF]

open access: yes
This paper proposes likelihood-based procedures for determining the number of cointegrating vectors in the presence of constraints on the cointegration rank.
Cavaliere Giuseppe   +2 more
core  

A Jackknife Correction to a Test for Cointegration Rank

open access: yesEconometrics, 2015
This paper investigates the performance of a jackknife correction to a test for cointegration rank in a vector autoregressive system. The limiting distributions of the jackknife-corrected statistics are derived and the critical values of these ...
Marcus J. Chambers
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Asymptotic Power Functions of Some Statistical Rank Order Tests [PDF]

open access: yesThe Egyptian Statistical Journal, 1957
S.R. Salib
doaj   +1 more source

Modeling Multivariate Distributions with Continuous Margins Using the copula R Package

open access: yesJournal of Statistical Software, 2010
The copula-based modeling of multivariate distributions with continuous margins is presented as a succession of rank-based tests: a multivariate test of randomness followed by a test of mutual independence and a series of goodness-of-fit tests.
Ivan Kojadinovic, Jun Yan
doaj  

Saddlepoint approximations for linear rank tests with left-truncated, right-censored, and cross-sectional data under randomized block design

open access: yesScientific Reports
Left-truncated data arise when events are only recorded if they occur after a pre-specified time point, while right censoring occurs when the exact event time is not fully observed.
Kholoud S. Kamal   +2 more
doaj   +1 more source

The Brier score does not evaluate the clinical utility of diagnostic tests or prediction models

open access: yesDiagnostic and Prognostic Research, 2017
Background A variety of statistics have been proposed as tools to help investigators assess the value of diagnostic tests or prediction models. The Brier score has been recommended on the grounds that it is a proper scoring rule that is affected by both ...
Melissa Assel   +2 more
doaj   +1 more source

Home - About - Disclaimer - Privacy