Results 121 to 130 of about 1,456,756 (304)
Molecular bases of circadian magnesium rhythms across eukaryotes
FEBS Letters, EarlyView.Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
Rank-Sum Tests for Dispersions
The Annals of Mathematical Statistics, 1960 This paper deals with non-parametric two-sample tests on dispersions. Two samples, $X$- and $Y$-samples of $m$ and $n$ independent observations from populations with continuous cumulative distribution functions $F(u)$ and $G(u)$ respectively, are considered.
Ansari, A. R., Bradley, R. A.
openaire +3 more sources
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
Nonparametric Rank Tests for Non-stationary Panels [PDF]
This study develops new rank tests for panels that include panel unit root tests as a special case. The tests are unusual in that they can accommodate very general forms of both serial and cross-sectional dependence, including cross-unit cointegration ...
Pedroni, Peter +3 more
core
Journal of the Royal Statistical Society Series B: Statistical Methodology, 1964 Summary Wilcoxon (1945, 1947) proposed a signed rank test for the hypothesis of equality of means in samples of n matched pairs of observations from a bivariate population in (x, y). He stated the exact distribution of the sum (= U +) of the signed ranks of the positive differences z = x - y, as well as providing some tables of the ...
openaire +2 more sources
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
Long-run validity of purchasing power parity and rank tests for cointegration for Central Asian Countries [PDF]
This study finds that Purchasing Power Parity holds in the long-run for Azerbaijan, Kazakhstan and Kyrgyzstan, based on Breitung’s (2001) rank tests for cointegration.
Chia, Ricky Chee-Jiun +2 more
core +1 more source
Statistical inference based on robust low-rank data matrix approximation
, 2014 The singular value decomposition is widely used to approximate data matrices with lower rank matrices. Feng and He [Ann. Appl. Stat. 3 (2009) 1634-1654] developed tests on dimensionality of the mean structure of a data matrix based on the singular value ...
Feng, Xingdong, He, Xuming
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Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Recovery of Low-Rank Plus Compressed Sparse Matrices with Application to Unveiling Traffic Anomalies
, 2012 Given the superposition of a low-rank matrix plus the product of a known fat compression matrix times a sparse matrix, the goal of this paper is to establish deterministic conditions under which exact recovery of the low-rank and sparse components ...
Giannakis, Georgios B. +2 more
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