Results 91 to 100 of about 90,081 (258)

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Enhancing mean estimators in median ranked set sampling with dual auxiliary information. [PDF]

Heliyon, 2023
Alharbi R, Mustafa MS, Al Mutairi A, Hussein M, Yusuf M, Elshenawy A, Nassr SG.   +6 more
europepmc   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

Estimation of Variance of Normal Distribution using Ranked Set Sampling

پژوهش‌های ریاضی, 2019
Introduction     In some biological, environmental or ecological studies, there are situations in which obtaining exact measurements of sample units are much harder than ranking them in a set of small size without referring to their precise values.
Narges Mahdavimanesh, Nasrollah Iranpanah, Ehsan Zamanzadeh   +2 more
doaj  

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Moving Set Size Ranked Set Sampling

International Journal of Statistics and Probability
A new variation of ranked set sampling technique, entitled "Moving set size ranked set sampling", (MSSRSS), is suggested. The suggested variation allows for the increase of the number of units that can be chosen by judgement. The suitability of this modified technique for the estimation of parameters of the underlying distribution of ...
Mohammad Fraiwan Al-Saleh, Hanan Youns Adam   +1 more
openaire   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Bayesian AEWMA control chart under ranked set sampling with application to reliability engineering. [PDF]

Sci Rep, 2023
Khan I, Noor-Ul-Amin M, Muhammad Khan D, Khalil U, Ismail EAA, Yasmeen U, Ahmad B.   +6 more
europepmc   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

A novel proposed class of estimators under ranked set sampling: Simulation and diverse applications. [PDF]

Heliyon, 2023
Yusuf M, Alsadat N, Oluwafemi Samson B, El Raouf MA, Alohali H.   +4 more
europepmc   +1 more source