Results 61 to 70 of about 97,870 (259)

Effect of DFPP on Ferroptosis in Peripheral Blood CD14+ Monocytes of Hyperlipidemic Patients Involving the ACSL4/LPCAT3/ALOX5 Pathway

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Hyperlipidemia is a major risk factor for atherosclerotic cardiovascular disease (ASCVD). Although statins are the cornerstone of lipid‐lowering therapy, their use may be limited in some patients by adverse effects. This study evaluated the possible impact of non‐drug treatment using double‐filtration plasmapheresis (DFPP) on CD14+
Yun Cheng, Lan Li, Qingmei Yang, Meipeng Wu   +3 more
wiley   +1 more source

New Modification of Ranked Set Sampling for Estimating Population Mean: Neutrosophic Median Ranked Set Sampling with an Application to Demographic Data

International Journal of Computational Intelligence Systems
The study addressed the limitations of classical statistical methods when dealing with ambiguous data, emphasizing the importance of adopting neutrosophic statistics as a more effective alternative.
Anamika Kumari, Rajesh Singh, Florentin Smarandache   +2 more
doaj   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Truncation-based median ranked set sampling with applications to breast cancer data

Frontiers in Applied Mathematics and Statistics
We propose truncation-based median ranked set sampling (TBMRSS). The estimator of the population mean and median is studied under this design. We show that the population mean estimator is unbiased for symmetric distributions.
Mohammed Obeidat
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Application to Road Traffic Accidents: An Almost Unbiased Estimator for Population Mean Under Ranked Set Sampling and Stratified Ranked Set Sampling

Journal of Statistical Theory and Applications (JSTA)
Ranked Set Sampling (RSS) serves as an effective and efficient alternative to Simple Random Sampling (SRS), especially when ranking items is easier than taking precise measurements. Stratified sampling is used for better estimation when the population is
Sunil Kumar Yadav, Rajesh Singh, Anamika Kumari   +2 more
doaj   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Bayesian mixture modelling with ranked set samples

Statistics in Medicine
We consider the Bayesian estimation of the parameters of a finite mixture model from independent order statistics arising from imperfect ranked set sampling designs. As a cost‐effective method, ranked set sampling enables us to incorporate easily attainable characteristics, as ranking information, into data collection and Bayesian estimation. To handle
Amirhossein Alvandi, Sedigheh Omidvar, Armin Hatefi, Mohammad Jafari Jozani, Omer Ozturk, Nader Nematollahi   +5 more
openaire   +3 more sources

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source