Results 151 to 160 of about 5,851,461 (307)
Directed evolution of enzymes at the crossroads of tradition and innovation
FEBS Open Bio, EarlyView.An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
FEBS Open Bio, EarlyView.Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya +2 more
wiley +1 more source
Ranking the ‘Diamond Core’ economic journals: A note [PDF]
By estimating the production frontier with the application of Data Envelopment Analysis (DEA) we rank the ‘Diamond Core’ economic journals as has been presented by Diamond (1989).
Halkos, George, Tzeremes, Nickolaos
core
Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells
FEBS Open Bio, EarlyView.Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim +4 more
wiley +1 more source
On the rank functions of $\mathcal{H}$-matroids
Journal of Algebra Combinatorics Discrete Structures and Applications, 2016 The notion of $\mathcal{H}$-matroids was introduced by U. Faigle and S. Fujishige in 2009 as a general model for matroids and the greedy algorithm. They gave a characterization of $\mathcal{H}$-matroids by the greedy algorithm. In this note, we give a characterization of some $\mathcal{H}$-matroids by rank functions.
openaire +4 more sources
Ranking function based on Higher Order Statistics (RF-HOS) for two-sample microarray experiments
, 2007 This paper proposes a novel ranking function, called RFHOS by incorporating higher order cumulants into the ranking function for finding differentially expressed genes.
Shaik, Jahangheer, Yeasin, Mohammed
core +1 more source
MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis
FEBS Open Bio, EarlyView.MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss +7 more
wiley +1 more source
Automatic Synthesis of Linear Program Ranking Functions
工程科学与技术, 2009 :Due to determining the classical ranking functions of program verification, a new approach was proposed based on the theory of semi-algebraic systems.
Li Jun, LI Yl, Feng Yong, Qin Xiao-lin
doaj
Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA
FEBS Open Bio, EarlyView.Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley +1 more source
Evolution‐guided yeast complementation reveals functional differences in human PSPH variants
FEBS Open Bio, EarlyView.Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez +6 more
wiley +1 more source