Results 141 to 150 of about 5,386,608 (256)

Enhanced parameter estimation for Lomax distribution using a contemporary triangular fuzzy ranking method

open access: yesMethodsX
This study presents a novel approach to parameter estimation for the Lomax distribution using a contemporary triangular fuzzy ranking method. The Lomax distribution is critical in reliability analysis and lifetime data modeling but often faces challenges
D. Kalpanapriya, Pullooru Bhavana
doaj   +1 more source

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

open access: yesFEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti   +5 more
wiley   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

open access: yesFEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain   +11 more
wiley   +1 more source

Using cell‐free RNA to identify B‐ and T‐cell clonality for diagnosis and monitoring of B‐ and T‐cell neoplasms

open access: yesFEBS Open Bio, EarlyView.
Using peripheral blood for determining B‐cell or T‐cell clonality is more reliable when we use cell‐free RNA (cfRNA) because cells release blood significantly more RNA than DNA. Next‐generation sequencing (NGS) of cfRNA allows us to evaluate fragment cfRNA and evaluate clonality reliably without the need for prior determination of the specific dominant
Adam Albitar   +11 more
wiley   +1 more source

Penyelesaian pemrograman linier fuzzy trapesium dengan Mmenggunakan metode ranking function [PDF]

open access: yes, 2017
INDONESIA Permasalahan pemrograman linier memiliki parameter antara lain jumlah produk yang harus diproduksi, jumlah bahan mentah yang tersedia terbatas atau jumlah tenaga kerja yang terampil terbatas.
Azizi, Fikri
core   +1 more source

A minimal cellulosome‐like system in Cellulosilyticum lentocellum

open access: yesFEBS Open Bio, EarlyView.
Cellulose‐degrading bacteria typically use cellulosomes, large multi‐enzyme complexes on a scaffold protein. In Cellulosilyticum lentocellum, we characterise a far smaller arrangement, a single scaffold bound to one cellulase through a single cohesin‐dockerin interaction.
John Allan   +2 more
wiley   +1 more source

THREE ULTIMATE RANKING VALUES AREN’T OUTGOING INTO ONE APIECE INTEGER FOR ULTIMATE RANKING METHOD WHICH IS USED QUALITY FUNCTION DEPLOYMENT IS ANALYSED WITH TOPSIS METHOD

open access: yesSakarya Üniversitesi İktisat Dergisi, 2017
The aim of this study is provided to make ranking values which aren’t outgoing into one apiece integer by using Ultimate Ranking Method that find meaning in Quality Function Deployment (QFD), analyse by TOPSIS method.
Osman Yakıt
doaj  

IGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo

open access: yesFEBS Open Bio, EarlyView.
To test whether endogenous IGF2 promotes osteosarcoma growth, IGF2 was knocked out in Saos2 cells via CRISPR‐Cas9. KO cells showed reduced proliferation in vitro, and knockout xenografts in mice reached only ~25% of wild‐type tumor volume. Insulin‐like growth factor 2 (IGF2) is implicated in osteosarcoma, but direct functional evidence of its role is ...
Shun Yao, Marco Archetti
wiley   +1 more source

Top ranking economics journals impact variability and a ranking update to the year 2002 [PDF]

open access: yes
In this paper I address four questions concerning the quality of scientific economic papers. First, I validate the ex-ante procedure of computing the average impact of economic papers by comparing its results with the expost values.
Pedro C. Vieira
core  

Five‐Year Outcomes of Laparoscopic Sphincter‐Preserving Surgery for Rectal Cancer: A Prospective Study in Elderly Vietnamese Patients

open access: yesAging and Cancer, EarlyView.
This prospective study demonstrates that laparoscopic sphincter‐preserving surgery is feasible for elderly patients. While overall survival reaches 70% at 5 years, advanced T‐stage and the omission of neoadjuvant therapy significantly drive recurrence, highlighting the need for personalized geriatric protocols despite logistical challenges.
Huu Duc Ho   +4 more
wiley   +1 more source

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