Results 341 to 350 of about 315,545 (404)

Response of UBR-box E3 ubiquitin ligases and protein quality control pathways to perturbations in protein synthesis and skeletal muscle size. [PDF]

Am J Physiol Cell Physiol
Baehr LM, Oliveira de Sousa LG, Goodman CA, Sharples AP, Waddell DS, Bodine SC, Hughes DC.   +6 more
europepmc   +1 more source

Structures and files for MD simulations of ternary complexes FKBP12-FRAP-rapamycin and FKBP12-CEP250-WDB002

Mathur, Apoorva
openalex   +1 more source

Piezo‐type mechanosensitive cation channel 1 in bone biomechanics and its multidimensional distribution characteristics in skeletal tissue

VIEW, EarlyView.
PIEZO1 is highly correlated with mechanical stimulation, controlling bone growth and remodeling, while showing specific distribution characteristics under distinct loads. Upon dialectical review, this manuscript proposes that PIEZO1 could serve as a target for osteoporosis and a quantitative indicator for monitoring bone health in real‐time.
Chunyu Zhang, Yuehong Wang
wiley   +1 more source

High-intensity running exercise promotes knee meniscal damage via the PI3K/AKT/mTOR axis. [PDF]

Bone Joint Res
Yao J, Ke H, Huang G, Wang X, Li Z, Shao Y, Chen H, Pan J, Cai D, Zeng C.   +9 more
europepmc   +1 more source

Glioma‑associated microglia and macrophages as a potential target for mTOR inhibition in glioblastoma. [PDF]

Mol Med Rep
Zeiner PS, Schulz M, Schomber J, Weinem JB, Lorenz NI, Sauer B, Roller B, Weber KJ, Luger AL, Berger A, Plate KH, Sevenich L, Steinbach JP, Mosa MH, Harter PN, Ronellenfitsch MW.   +15 more
europepmc   +1 more source

Modulation of mTOR Within Retinal Pigment Epithelium Affects Cell Viability and Mitochondrial Pathology. [PDF]

Int J Mol Sci
Lazzeri G, Ferrucci M, Lenzi P, Giambelluca MA, Biagioni F, Busceti CL, Frati A, Fornai F.   +7 more
europepmc   +1 more source

Nociceptor deletion of Tsc2 enhances axon regeneration by inducing a conditioning injury response in dorsal root ganglia [PDF]

, 2019
Carlin, Dan, Cavalli, Valeria, Ewan, Eric E, Halevi, Alexandra E, Moore, Amy M   +4 more
core   +1 more source

Rapamycin suppresses small bowel adenocarcinoma HUTU 80 cells proliferation by inhibiting hypoxia-inducible factor-1α mediated metabolic reprogramming. [PDF]

World J Gastrointest Oncol
Pu BP, Wang PH, Guo KK, Liu C, Chen SR, Li XM, Chen SM, Zeng XZ, Gao C.   +8 more
europepmc   +1 more source