Results 201 to 210 of about 5,593,091 (310)

Facilely Synthesized Rough Photothermal Gold Nanoparticles for Portable and Rapid Detection of <i>Staphylococcus aureus</i>. [PDF]

Biosensors (Basel)
Lv Z, Tan X, Chen P, Qu M, Guo W, Huang J, Cui X.   +6 more
europepmc   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Novel surveillance design exploiting network analysis for efficient, rapid detection of emerging Clostridioides difficile strains. [PDF]

Nat Commun
Pople D, Donker T, Nsonwu O, Jeyaratnam D, Chudasama D, Hope R, Hopkins S, Wilcox MH, Eyre DW, Walker AS, Robotham JV.   +10 more
europepmc   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Development of a Colourimetric Loop-Mediated Isothermal Amplification Assay for Rapid Detection of Streptococcus dysgalactiae. [PDF]

J Fish Dis
Lau TV, Puah SM, Chua KH.
europepmc   +1 more source

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

FEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro, Fernando Lucas Palhano   +1 more
wiley   +1 more source

Time-Multiplexed Organic Electrochemical Transistor for Saliva-Based Rapid Detection of Viral Proteins. [PDF]

Adv Sci (Weinh)
Chang T, Ren Y, Wustoni S, Alqatari A, Hama A, Wang Y, Chen L, Agudelo JP, Salvigni L, Guo K, Dada A, Arold ST, Grünberg R, Inal S.   +13 more
europepmc   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Rapid detection and quantification of sweet potato storage roots using ground penetrating radar. [PDF]

Plant Phenomics
Tei M, Liu J, Gomez C, Ishii T, Uga Y.
europepmc   +1 more source