Results 131 to 140 of about 953,634 (315)

The clinical utility of Nanopore 16S rRNA gene sequencing for direct bacterial identification in normally sterile body fluids

Frontiers in Microbiology
The prolonged incubation period of traditional culture methods leads to a delay in diagnosing invasive infections. Nanopore 16S rRNA gene sequencing (Nanopore 16S) offers a potential rapid diagnostic approach for directly identifying bacteria in infected
Hiu-Yin Lao, Lily Lok-Yee Wong, Yan Hui, Timothy Ting-Leung Ng, Chloe Toi-Mei Chan, Hazel Wing-Hei Lo, Miranda Chong-Yee Yau, Eddie Chi-Man Leung, River Chun-Wai Wong, Alex Yat-Man Ho, Kam-Tong Yip, Jimmy Yiu-Wing Lam, Viola Chi-Ying Chow, Kristine Shik Luk, Tak-Lun Que, Franklin Wang Ngai Chow, Gilman Kit-Hang Siu   +16 more
doaj   +1 more source

Introducing new diagnostics into STI control programmes: the importance of programme science.

, 2013
Many innovative diagnostic technologies will become commercially available over the next 5-10 years. These tests can potentially transform the diagnosis of sexually transmitted infections but their introduction into control programmes can be hampered by ...
Mabey, David, Peeling, Rosanna W, Ballard, Ronald C   +2 more
core   +1 more source

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi, Lara Basovic, Christopher Michael McGraw   +2 more
wiley   +1 more source

Graphene-Based Virus Enrichment Protocol Increases the Detection Sensitivity of Human Norovirus in Strawberry and Oyster Samples

Foods
Human noroviruses (HuNoVs), the most prevalent viral contaminant in food, account for a substantial proportion of nonbacterial gastroenteritis cases. Extensive work has been focused on the diagnosis of HuNoVs in clinical samples, whereas the availability
Shuqing Zhou, Min Jin, Jing Yin, Danyang Shi, Haibei Li, Zhixian Gao, Zhengshan Chen, Zhongwei Yang, Tianjiao Chen, Huaran Wang, Junwen Li, Dong Yang   +11 more
doaj   +1 more source

Spinal Cord Infarction Versus Idiopathic Transverse Myelitis: Clinical, Radiological, and Functional Insights From a Retrospective Cohort Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Spinal cord infarction (SCI) is a rare but devastating myelopathy, characterized by a high disability rate and an unfavorable prognosis. It has often been underdiagnosed and misdiagnosed as idiopathic transverse myelitis (ITM). This study aimed to describe the clinical features, radiological biomarkers, treatments, and functional ...
Zeqiang Ji, Jianlong Zhang, Yiming Shi, Shiyu Shan, Yang Du, Guangshuo Li, Ying Jin, Yani Zhang, Chuanying Wang, Yijun Lin, Yuhao Guo, Decai Tian, Xingquan Zhao, Tian Song   +13 more
wiley   +1 more source

Clustering Algorithm Reveals Dopamine‐Motor Mismatch in Cognitively Preserved Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore the relationship between dopaminergic denervation and motor impairment in two de novo Parkinson's disease (PD) cohorts. Methods n = 249 PD patients from Parkinson's Progression Markers Initiative (PPMI) and n = 84 from an external clinical cohort.
Rachele Malito, Chiara Meneghini, Alice Galli, Luca Gallo, Pierfrancesco Mitrotti, Paola Dimartino, Marianna Inglese, Cinzia Zatti, Alessandro Lupini, Andrea Pilotto, Alessandro Padovani, Micol Avenali, Enza Maria Valente, Cristina Tassorelli, Silvia P. Caminiti   +14 more
wiley   +1 more source

Early diagnosis of Pearson syndrome in neonatal intensive care following rapid mitochondrial genome sequencing in tandem with exome sequencing

, 2019
Rapid genomic testing is a valuable new diagnostic tool for acutely unwell infants, however exome sequencing does not deliver clinical-grade mitochondrial genome sequencing and may fail to diagnose mitochondrial disorders caused by mitochondrial DNA ...
Lunke, Sebastian, Eggers, Stefanie, Zornitza Stark, Tiong Y. Tan, Akesson, Lauren S, John Christodoulou, Christodoulou, John, David R. Thorburn, Sebastian Lunke, Matthew F. Hunter, Richmond, Christopher M, Christopher M. Richmond, Love, Clare J, Belinda Chong, Tan, Tiong Y, Thorburn, David R, Clare J. Love, Stefanie Eggers, Chong, Belinda, Hunter, Matthew F, Brown, Natasha J, Krzesinski, Emma I, Emma I. Krzesinski, Lauren S. Akesson, Natasha J. Brown, Stark, Zornitza   +25 more
core   +1 more source

Brainstem and Cerebellar Volume Loss and Associated Clinical Features in Progressive Supranuclear Palsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Progressive Supranuclear Palsy (PSP) is a neurodegenerative ‘tauopathy’ with predominating pathology in the basal ganglia and midbrain. Caudal tau spread frequently implicates the cerebellum; however, the pattern of atrophy remains equivocal.
Chloe Spiegel, Timothy P. Siejka, Cassandra Marotta, Josh J. Y. Lee, Kelly Bertram, Terence J. O'Brien, Meng Law, Lucy Vivash, Ian H. Harding   +8 more
wiley   +1 more source

Role of urine reagent strips in early diagnosis of meningitis [PDF]

Journal of Krishna Institute of Medical Sciences University
Background: Early diagnosis of meningitis is critical to reducing associated morbidity and mortality, especially in resource-limited settings. Conventional Cerebrospinal Fluid (CSF) analysis is accurate but time-consuming.
Preeti Singh, Vijay Kumar Jaiswal, Neha Singh, Anamika Singh Thakur   +3 more
doaj  

Development of rapid, automated diagnostics for infectious disease: advances and challenges

, 2009
The last 2 years has seen an exponential rise in the amount of research funding made available for the development of rapid diagnostic devices for infectious agents of medical importance. This review reports on several such projects.
Ince, J, McNally, A
core   +1 more source