Results 111 to 120 of about 953,634 (315)

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

RAPID DIAGNOSIS OF MALARIA

The Lancet, 1989
L S, Rickman, G W, Long, S L, Hoffman
  +7 more sources

Effective Dexmedetomidine Dose for Stage N2 Sleep Induction and Associated Factors in Depression-Related Insomnia: A Polysomnography-Based Analysis

Nature and Science of Sleep
Yaozu Li,1– 4 Muyan Zuo,1– 4 Ruoguo Wang,2,3 Yongxiang Li,2,3 John P Williams,5 Jianxiong An1– 5 1Medical School, University of Chinese Academy of Sciences, Beijing, People’s Republic of China; 2Center for Pain & Sleep Medicine, Affiliated Hospital ...
Li Y, Zuo M, Wang R, Li Y, Williams JP, An J   +5 more
doaj  

Hydrostatic pressure activates HIF‐1α via β‐catenin to promote stemness in breast cancer cells

FEBS Open Bio, EarlyView.
To mimic the elevated intestinal fluid pressure in breast cancers, we loaded human breast cancer cells (MCF‐7, MDA‐MB‐453, and BT‐474) to 50 mmHg hydrostatic pressure. Hydrostatic pressure exposure upregulated HIF‐1α and induced stemness in MCF‐7 and BT‐474 cells.
Da Zhai, Yong Xu, Jingjing Ma, Ratchanee Duangrat, Chen Yan, Jingyan Liang, Hua Wei, Bin Jiang, Tao‐Sheng Li   +8 more
wiley   +1 more source

Malaria misdiagnosis in Uganda--implications for policy change. [PDF]

, 2009
BACKGROUND: In Uganda, like in many other countries traditionally viewed as harbouring very high malaria transmission, the norm has been to recommend that febrile episodes are diagnosed as malaria.
Zurovac, D, John B Rwakimari, Rwakimari, JB, Njogu, JN, Counihan, HC, Rwakimari John B, Snow, Robert, Nankabirwa, Joan, Counihan Helen, Rwakimari, John B., Snow, Robert W, Nankabirwa, JI, Tibenderana, James K., Tibenderana, JK, Njogu Julius N, Njogu, Julius N., Snow, RW, Counihan, Helen, Robert W Snow, Snow Robert W, Snow, Robert W., Zurovac Dejan, Counihan, H, Tibenderana, James K, Rwakimari, John B, Njogu, Julius N, Nankabirwa Joan, Zurovac, Dejan, Nankabirwa, J, Julius N Njogu, Helen Counihan, James K Tibenderana, Tibenderana James K, Joan Nankabirwa, Dejan Zurovac   +34 more
core   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Multiplex real-time reverse transcription recombinase-aided amplification assay for the detection of SARS-CoV-2, influenza A virus, and respiratory syncytial virus

Microbiology Spectrum
Influenza A virus (IAV), severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), and respiratory syncytial virus (RSV) are significant pathogens that induce respiratory symptoms in humans, significantly impacting healthcare systems, economic ...
Yuandong Zhou, Chudan Liang, Zhenyu Long, Linjin Fan, Yulong Wang, Zequn Wang, Xiaofeng Yang, Pengfei Ye, Jingyan Lin, Wendi Shi, Huijun Yan, Linna Liu, Jun Qian   +12 more
doaj   +1 more source

Evaluating the cost-effectiveness of artemisinin-based combination antimalarial drugs and malaria rapid diagnostic tests within the context of effective vector control : case study of Southern Africa

, 2006
Includes bibliographical references (p. 253-265)This study seeks to use the techniques of cost-effectiveness analysis to evaluate, within the context of effective vector control, the change to artemisinin-based combination therapies (ACTs) as first ...
Zikusooka, Charlotte Muheki
core  

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

An overview of rapid non-culture-based techniques in various clinical specimens for the laboratory diagnosis of Talaromyces marneffei

Frontiers in Cellular and Infection Microbiology
Talaromyces marneffei (T. marneffei) is a temperature-dependent biphasic deep opportunistic infectious fungus that primarily affects individuals with advanced HIV disease and other immunocompromised populations.
Huamei Wei, Huamei Wei, Patcharin Thammasit, Artid Amsri, Artid Amsri, Kritsada Pruksaphon, Fenglian Deng, Joshua D. Nosanchuk, Sirida Youngchim   +8 more
doaj   +1 more source