Results 51 to 60 of about 1,045,227 (267)

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Interpreting rapid diagnostic test (RDT) for Plasmodium falciparum

BMC Research Notes, 2018
Objective Rapid diagnostic tests have been of tremendous help in malaria control in endemic areas, helping in diagnosis and treatment of malaria cases. It is heavily relied upon in many endemic areas where microscopy cannot be obtained.
Verner N. Orish, Virtue F. De-Gaulle, Adekunle O. Sanyaolu   +2 more
doaj   +1 more source

Getting antimalarials on target: impact of national roll-out of malaria rapid diagnostic tests on health facility treatment in three regions of Tanzania. [PDF]

, 2013
OBJECTIVES: Parasitological confirmation of malaria prior to treatment is recommended for patients of all ages, with malaria rapid diagnostic tests (mRDTs) an important tool to target artemisinin-based combination therapies (ACTs) to patients with ...
Bruxvoort, Katia, Cairns, Matthew, Festo, Charles, Goodman, Catherine, Kachur, S Patrick, Kalolella, Admirabilis, Kleinschmidt, Immo, Nchimbi, Happy, Taylor, Mark, Thomson, Rebecca, Thwing, Julie   +10 more
core   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Mobile phones improve case detection and management of malaria in rural Bangladesh

Malaria Journal, 2013
Background The recent introduction of mobile phones into the rural Bandarban district of Bangladesh provided a resource to improve case detection and treatment of patients with malaria.
Prue Chai S, Shannon Kerry L, Khyang Jacob, Edwards Laura J, Ahmed Sabeena, Ram Malathi, Shields Timothy, Hossain Mohammad S, Glass Gregory E, Nyunt Myaing M, Sack David A, Sullivan David J, Khan Wasif A   +12 more
doaj   +1 more source

Immunochromatographic diagnostic test analysis using Google Glass. [PDF]

, 2014
We demonstrate a Google Glass-based rapid diagnostic test (RDT) reader platform capable of qualitative and quantitative measurements of various lateral flow immunochromatographic assays and similar biomedical diagnostics tests.
Caire, Romain, Cortazar, Bingen, Feng, Steve, Ozcan, Aydogan, Turan, Mehmet, Wong, Andrew   +5 more
core   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

SARS-CoV-2 Antigen Rapid Test in The Emergency Department; a Diagnostic Accuracy Study

طب اورژانس ایران, 2023
Title: Evaluation of diagnostic value of SARS-CoV-2 rapid diagnostic test in patients with Covid-19 Introduction: The standard RT-PCR test is a time-consuming diagnostic test with difficult accessibility and high cost, so in order to early diagnose ...
Saeed Safari, Faezeh Golpour, Mohammad Mehdi Forouzanfar, Behrooz Hahsemi, Shahram Ebrahimi   +4 more
doaj   +1 more source

Uji Diagnostik Cepat Sebagai Metode Alternatif Diagnosis Kholera Yang Disebabkan Oleh Agen Vibrio Cholera [PDF]

, 2015
Cholera is one of health problems in Indonesia. The high fatality rate is caused by the enterotoxin. The symptoms are dehydration, electrolyte loss and increased blood acidity, so that in severe case can cause death. Diarrheal disease cholera can lead to
Putranto, R. H. (Rudi), Sariadji, K. (Kambang), Sunarno, S. (Sunarno)   +2 more
core  

Field evaluation of two point-of-care tests for syphilis among men who have sex with men, Verona, Italy [PDF]

, 2017
Objectives: The incidence of HIV and syphilis among men who have sex with men (MSM) in Europe has recently increased. Rapid point-of-care tests (POCTs) for syphilis can improve access to screening.
Ballard, Ronald, Blondeel, Karel, Cordioli, Maddalena, Cornaglia, Giuseppe, Del Bravo, Paola, Gios, Lorenzo, Kiarie, James, Mirandola, Massimo, Peeling, Rosanna W, Toskin, Igor, Zorzi, Antonella   +10 more
core   +2 more sources