Results 71 to 80 of about 7,879,048 (280)
Using RP to promote collaborative design of customised medical implants
, 2007 Published ArticleThe last decade has seen major advances in rapid prototyping (RP), with it becoming a multi‐disciplinary technology, crossing various research fields, and connecting continents.
Campbell, R. Ian +6 more
core
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Three‐dimensional plotting as a visualisation aid for architectural use
, 2004 Published ArticleFunctional design is closely linked to manufacturing and building. Designers' freedom to express themselves is often limited by the capabilities of craftsmen who have to give physical substance to the designer's ideas. This paper reviews
Booysen, Gerrie J. +2 more
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Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Printing Press, Rapid City SD, Pennington County
4 x 5 photograph, a printing pressTowns Provo - Rapid City P35 Tab R Poster board Rapid City P35 [stamp] Property of South Dakota State Historical Society Pierre, South Dakota [stamp] Give photo credit to: South Dakota State Historical Society.
Rapid City Journal
core +1 more source
PlantsAgricultural production faces critical challenges in arid regions due to global climate change and water scarcity. Exploring optimal water and nitrogen irrigation combinations is essential to enhancing water use efficiency and crop yields.
Tao Zhu +4 more
doaj +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Profiling the life course of resource-based boomtowns: A key step in crime prevention
Journal of Community Safety and Well-Being, 2018 -
Rick Ruddell, Heather A. Ray
doaj +1 more source
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Challenges of NTM Drug Development
Frontiers in Microbiology, 2018 Discovery and development of antibiotics active against the environmental opportunistic non-tuberculous mycobacteria (NTM) have been retarded by innate antibiotic-resistance of NTM cells and methodological challenges in the laboratory.
Joseph O. Falkinham
doaj +1 more source