Results 81 to 90 of about 3,798,437 (293)

A Model of Technology Transfer in Japan's Rapid Economic Growth Period [PDF]

Why did the Japanese economy stagnate beforeWorldWar II, how did it achieve rapid economic growth after the war, and why did it stagnate again after the 1970s?
Aoki, Shuhei
core  

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Impact of Drip Irrigation and Nitrogen Application on Plant Height, Leaf Area Index, and Water Use Efficiency of Summer Maize in Southern Xinjiang

Plants
Agricultural production faces critical challenges in arid regions due to global climate change and water scarcity. Exploring optimal water and nitrogen irrigation combinations is essential to enhancing water use efficiency and crop yields.
Tao Zhu, Feng Liu, Guangning Wang, Han Guo, Liang Ma   +4 more
doaj   +1 more source

Cambodia 1998-2008 : an episode of rapid growth [PDF]

Cambodia's growth over 1998-2008 has been remarkable (almost 10 percent per annum for a decade). This paper applies a"growth diagnostic"approach to understand how this happened and how it can be sustained.
Guimbert, Stephane
core  

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Profiling the life course of resource-based boomtowns: A key step in crime prevention

Journal of Community Safety and Well-Being, 2018
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Rick Ruddell, Heather A. Ray
doaj   +1 more source

Assessing the determinants of fast growth in Italy [PDF]

Few firms grow in a rapid way, but their contribution to employment growth is often impressive. The main purpose of this paper is to analyze both external and internal factors which can affect the probability of being a high-growth firm (HGF) in Italy ...
A. Arrighetti, A. Lasagni
core  

Morphology and Nanomechanics of Sensory Neurons Growth Cones following Peripheral Nerve Injury [PDF]

, 2012
A prior peripheral nerve injury in vivo, promotes a rapid elongated mode of sensory neurons neurite regrowth in vitro. This in vitro model of conditioned axotomy allows analysis of the cellular and molecular mechanisms leading to an improved neurite re ...
A Nilsson, A Vinckier, AB Huber, AB Mathur, AL Weisenhorn, AR Bausch, Attila-Gergely Végh, B Geiger, C Hilaire, ChC Dupont-Gillain, Csilla Gergely, DM Suter, DS Smith, E Evans, E Spedden, EW Dent, F Charron, Frédérique Scamps, H-J Butt, HA McNally, HA McNally, HJ Song, HS Xiao, I Mechaly, Igor Sokolov, IN Sneddon, J Dai, J Laishram, J Sleep, JL Goldberg, K Tanaka, KD Costa, L Lankford K, M Mustata, M Radmacher, M Radmacher, Marta Martin, MG Hertz, MJ Rosenbluth, Olivier Lucas, Ouafa Benzina, OV Chumakova, PN Hoffman, R García, R Lal, S Andre, S Pieraut, S Pieraut, SS Hannila, T Araki, T Tojima, TC Dickson, Thierry Cloitre, TS Lanero, V Heinrich, Vivien Szabo, Y Xiong, ZL Chen   +57 more
core   +5 more sources

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

Challenges of NTM Drug Development

Frontiers in Microbiology, 2018
Discovery and development of antibiotics active against the environmental opportunistic non-tuberculous mycobacteria (NTM) have been retarded by innate antibiotic-resistance of NTM cells and methodological challenges in the laboratory.
Joseph O. Falkinham
doaj   +1 more source