Results 41 to 50 of about 25,263,200 (250)
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Pediatric Rapid Response Systems: A preliminary Analysis of Evaluative Processes
, 2019 The efficacy of decreasing mortality rates with rapid response systems (RRS) have recently been disputed. A problem exists in the lack of knowledge of the efficacy and the most appropriate way to evaluate rapid response systems.
Burnett, Sarah
core
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Physical modeling of catchment area by rapid prototyping using GIS data
, 2006 Published ArticleThe purpose of the present work is to develop a methodology for making physical models of catchment areas and terrains by rapid prototyping (RP) using geographic information systems (GIS) data.
Theron, Elizabeth +4 more
core
Exogenous Rapid response subsystem
, 2016 Rapid response component of the exogenous reflexive system. Key components of this subsystem are a detector for rapid onset stimuli, the triggering of startle behavior, and mechanisms that prevent repeated startle behavior (“startleRefractory”) and the ...
Ulysses Bernardet (2744284)
core +1 more source
Rapid kinetics of agonist binding and permeability response analyzed in parallel on acetylcholine receptor rich membranes from Torpedo marmorata [PDF]
, 1983 Heidmann T, Bernhardt J, Neumann E, Changeux JP. Rapid kinetics of agonist binding and permeability response analyzed in parallel on acetylcholine receptor rich membranes from Torpedo marmorata. Biochemistry.
Changeux, Jean Pierre +3 more
core +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Introduction: Rapid response mechanisms—strengthening defense cooperation and saving strangers?
, 2019 The track record of military rapid response mechanisms, troops on standby, ready to be deployed to a crisis within a short time frame by intergovernmental organizations, remains disappointing.
Reykers, Yf, Karlsrud, John
core
, 2014 Rapid Telecommunications Assessment Team (RTAT) Web site: https://www.roddenberrydrt-handbook.com/rtat.htmlThe primary mission of the Roddenberry Disaster Response Team is clean water production, but we have also established a partnership with NetHope ...
Steckler, Brian, Beeson, R. Travis
core +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source