Results 51 to 60 of about 25,263,200 (250)

Rapid Manufacturing of Patient-specific Shielding Masks, using RP in parallel with Metal Spraying

open access: yes, 2005
Published ArticleThe purpose of the present work is to develop a methodology to manufacture patient‐specific models (lead masks) to be used as protective shields during cancer treatment, using 3D photography, rapid prototyping (RP) and metal spraying. It
Booysen, Gerrie J.   +4 more
core  

Issue Brief: Developing a ‘Rapid-response’ Program for Health System Decision-makers in Canada [PDF]

open access: yes, 2014
An assessment of what is known about problems related to developing a 'rapid response' program, options for addressing these problems, and key implementation considerations.
Wilson, MG   +2 more
core   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

Rapid response system (RRS) events in High Risk OSA patients versus Low Risk OSA patients.

open access: yes, 2016
Rapid response system (RRS) events in High Risk OSA patients versus Low Risk OSA patients.
Stuart F. Quan (333554)   +5 more
core   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

The Impact of Delayed Rapid Response System Activation

open access: yes
The timely deployment of intervention by the rapid response team is crucial to patient safety. Even short delays in response are associated with increased patient risk.
Føns-Sønderskov, Morten   +5 more
core   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

The microbiome in human skin aging

open access: yesFEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana   +3 more
wiley   +1 more source

Conclusion: Military rapid response—from institutional investment to ad hoc solutions

open access: yes, 2019
While there has been a mushrooming of institutional arrangements for military rapid response, the formal deployments of the rapid response mechanisms of the African Union (AU), European Union (EU), and North Atlantic Treaty Organization (NATO) are few ...
Reykers, Yf, Karlsrud, John
core  

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

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