Results 151 to 160 of about 362,520 (285)

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Effectiveness of adjunctive interventions in patients undergoing rapid maxillary expansion: An umbrella review

Journal of International Medical Research
Background Rapid maxillary expansion is widely used to correct transverse maxillary deficiency; however, its biological limitations have led to the use of adjunctive interventions, with inconsistent evidence regarding their effectiveness.
Ahmad Marwan Alhamwi, Ahmad S Burhan, Fehmieh R Nawaya   +2 more
doaj   +1 more source

Rapid Review

Journal of Clinical Gastroenterology, 2020
Ehrenpreis, Eli D., Kruchko, David H.
openaire   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Medication-related infrastructure and medication reviews in nursing homes—a rapid appraisal study

BMC Health Services Research
Background Around 86% of Switzerland’s nursing home (NH) residents have polypharmacy (≥ 5 concomitant medications); almost 80% use a potentially inappropriate medication increasing their risk of medication-related problems.
Carla Meyer-Massetti, Magdalena Osińska, Naomi Welte, Franziska Zúñiga   +3 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Software selection in large-scale software engineering: A model and criteria based on interactive rapid reviews. [PDF]

Empir Softw Eng, 2023
Bjarnason E, Åberg P, Ali NB.
europepmc   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

Appraising the current landscape of reviews on mpox vaccination: a rapid evidence map

Discover Public Health
Introduction Vaccination is a potent countermeasure for interrupting the spread of mpox, which is currently a priority public health problem in Africa. Backed by emergency declarations from both the World Health Organization (WHO) and the Africa Centres ...
Abdu A. Adamu, Joseph Okeibunor, Patrick D. M. C. Katoto, Reena H. Doshi, Duduzile Ndwandwe, Rabiu I. Jalo, Sidy Ndiaye, Samuel Boland, Charles S. Wiysonge   +8 more
doaj   +1 more source

Introducing PROCEED: a new service for fast registration and publication of protocols for environmental evidence syntheses, including Rapid Reviews. [PDF]

Environ Evid, 2023
Pullin A.
europepmc   +1 more source