Results 71 to 80 of about 362,520 (285)

Anaesthetic Mouthpiece Development through QFD and Customer Interaction with Functional Prototypes [PDF]

, 2006
Published ArticleThe paper reflects on the development of a medical product using rapid prototyping technologies and customer interaction through a quality function deployment (QFD) approach to speed up the process, and to result in customer satisfaction.
Truscott, M., Booysen, G.J., Barnard, L.J., de Beer, D.J.   +3 more
core  

Sustained Therapeutic Efficacy of Intravenous Plasminogen Concentrate in Pediatric Patients With Type 1 Plasminogen Deficiency: An Analysis of Dosing Parameters and Clinical Outcomes

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Type 1 plasminogen deficiency (PLGD‐1) is an ultra‐rare autosomal recessive disorder caused by variants in the PLG gene and affects approximately 1.6 individuals per million. The condition is characterized by decreased plasminogen levels and impaired function, resulting in fibrin‐rich lesions on mucous membranes throughout the body.
Charles Nakar, Karen Thibaudeau, Mary Mathias, Heather McDaniel, Madlen Reschke, Klaus Tenbrock, Joseph M. Parker, Amy Shapiro   +7 more
wiley   +1 more source

Reflections on conducting rapid reviews of educational research [PDF]

, 2022
Background: Rapid reviews involve a streamlined approach to knowledge synthesis. They are used to identify high-quality evidence for the purpose of informing decisions and initiatives, completed over relatively short timeframes, and have been found to ...
Walsh, L (15757415), Cutler, B (15757424), Gleeson, J (15757418), Salisbury, M (15757421), Constance Cirkony (14733808), Rickinson, M (15757412)   +5 more
core   +4 more sources

Critical appraisal in rapid systematic reviews of COVID-19 studies: implementation of the Quality Criteria Checklist (QCC)

Systematic Reviews, 2023
In this letter, we briefly describe how we selected and implemented the quality criteria checklist (QCC) as a critical appraisal tool in rapid systematic reviews conducted to inform public health advice, guidance and policy during the COVID-19 pandemic ...
Daphne Duval, Nicola Pearce-Smith, Jennifer C. Palmer, Jason Kwasi Sarfo-Annin, Paul Rudd, Rachel Clark   +5 more
doaj   +1 more source

Personalized Zebrafish Models for Fusion‐Positive Pediatric Sarcomas

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Clinical sequencing efforts have revolutionized our approaches to categorizing pediatric cancers in real time. This has dramatically improved our ability to profile pediatric tumors, identify actionable vulnerabilities, and influence clinical care.
Lisa H. Hall, Emma N. Harrison, Genevieve C. Kendall   +2 more
wiley   +1 more source

Development of rapid guidelines: 2. A qualitative study with WHO guideline developers

Health Research Policy and Systems, 2018
Background Situations such as public health emergencies and outbreaks necessitate the development and publication of high-quality recommendations within a condensed timeframe.
Ivan D. Florez, Rebecca L. Morgan, Maicon Falavigna, Sérgio C. Kowalski, Yuan Zhang, Itziar Etxeandia-Ikobaltzeta, Nancy Santesso, Wojtek Wiercioch, Holger J. Schünemann   +8 more
doaj   +1 more source

Rapid review: Reflective Practice in crisis situations

, 2020
This report presents a rapid review of the evidence on reflective practice in crisis situations.In the light of the current Covid-19 pandemic we asked the question “What lessons can we learn about the value of reflective practice that may be of service to our health professionals on the front line”.A search of Scopus (with no date restrictions was made.
Karen Rodham, Kiran Bains, Juliette Westbrook, Natalia Stanulewicz, Lucie Byrne-Davis, Jo Hart, Angel Chater   +6 more
openaire   +3 more sources

The Role of “Adult‐Onset” Cancer Predisposition Genes in Pediatric Cancer: A Comprehensive Review

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Current literature estimates that 10% of pediatric cancers are caused by pathogenic or likely pathogenic (P/LP) germline variants in cancer predisposition genes (CPGs). Variants in CPGs thought to increase cancer risk exclusively during adulthood are referred to as “adult‐onset” CPGs (aoCPGs).
Maria Rozo, Miriam A. Bornhorst, Angela J. Waanders, Sara Zarnegar‐Lumley, Ashwin Lakshman Koppayi, Lucy A. Godley   +5 more
wiley   +1 more source

Development of rapid guidelines: 1. Systematic survey of current practices and methods

Health Research Policy and Systems, 2018
Background Guidelines in the healthcare field generally should contain evidence-based recommendations to inform healthcare decisions. Guidelines often require 2 years or more to develop, but certain circumstances necessitate the development of rapid ...
Sergio C. Kowalski, Rebecca L. Morgan, Maicon Falavigna, Iván D. Florez, Itziar Etxeandia-Ikobaltzeta, Wojtek Wiercioch, Yuan Zhang, Faria Sakhia, Liudmila Ivanova, Nancy Santesso, Holger J. Schünemann   +10 more
doaj   +1 more source

Early Impact of Childhood Opportunity on Neurocognitive Outcomes in Sickle Cell Disease

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Neurocognitive impairment is a well‐recognized complication of sickle cell disease (SCD) that begins early in childhood and persists across development. While cerebrovascular injury contributes substantially to risk, neurocognitive deficits are also observed in children without overt or silent cerebral infarctions, suggesting ...
Julia E. LaMotte, Hannah Koch, Olivia A. Coughlin, Jillian R. Bouck, Allie Carter, Seethal A. Jacob   +5 more
wiley   +1 more source