Results 61 to 70 of about 1,789,575 (241)
Rapid manufacturing- state of the art, analysis and future perspectives [PDF]
, 2011 Layer based manufacturing system often referred to as Rapid Prototyping (RP) have been in existence for 22 years, in the past 5 years Rapid Manufacturing (RM) has emerged from these RP systems to produce functional and structural customer focused end use
Ainsley, Christopher, Hackney, Philip
core
Functional copmponents produced by multi-jet modelling combined with electroforming and machining
South African Journal of Industrial Engineering, 2014 In fuel cell technology, certain components are used that are responsible for guiding liquid media. When these components are produced by conventional manufacturing, there are often sealing issues, and trouble- and maintenance-free deployment cannot be ...
Baier, Oliver, Witt, Gerd
doaj +1 more source
Current Directions in Biomedical Engineering, 2021 Here, we demonstrate a manufacturing process for individualised, small-sized implant prototypes. Our process is promising for the manufacturing of drug-releasing (micro)implants to be implanted in the round window niche (RWN-I, solid body, free-form ...
Mau Robert +9 more
doaj +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Rapid Tooling via Stereolithography
, 2006 Approximately three years ago, composite stereolithography (SL) resins were introduced to the marketplace, offering performance features beyond what traditional SL resins could offer.
Montgomery, Eva
core
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Recent Research Progress and Future Perspectives of Additively Fabricated Abrasive Tools
Journal of Machine EngineeringAdditive technologies are becoming increasingly important in the fabrication of innovative tools. Currently, 3D printing methods based on flexible materials in various forms are being successfully used in the production of tools dedicated for precision ...
Dawid Zieliński +4 more
doaj +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Direct rapid tooling: a review of current research
Rapid prototyping technologies are now evolving toward rapid tooling. The reasons for this extension are found in the need to further reduce the time-to-market by shortening not only the development phase, but also the industrialization phase of the ...
Karapatis, N. P. +2 more
core +1 more source