Results 81 to 90 of about 38,509 (306)

Integration of CAD and rapid manufacturing for sand casting optimisation [PDF]

open access: yes, 2003
International audienceIn order to reduce the time and costs of the products development in the sand casting process, the SMC Colombier Fontaine company has carried out a study based on tooling manufacturing with a new rapid prototyping process.
Bernard, Alain   +3 more
core   +4 more sources

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Functional copmponents produced by multi-jet modelling combined with electroforming and machining

open access: yesSouth African Journal of Industrial Engineering, 2014
In fuel cell technology, certain components are used that are responsible for guiding liquid media. When these components are produced by conventional manufacturing, there are often sealing issues, and trouble- and maintenance-free deployment cannot be ...
Baier, Oliver, Witt, Gerd
doaj   +1 more source

INEL Spray-forming Research [PDF]

open access: yes, 1992
Spray forming is a near-net-shape fabrication technology in which a spray of finely atomized liquid droplets is deposited onto a suitably shaped substrate or mold to produce a coherent solid.
Key, James F., Mchugh, Kevin M.
core   +1 more source

Selective Laser Sintering Process Management Using a Relational Database [PDF]

open access: yes, 1999
With more and more materials used in the Selective Laser Sintering (SLS) process, it is becoming necessary to use a database to manage the process efficiently. In this paper, a relational database for the SLS process is described. The database includes
Gibson, Ian, Shi, Dongping
core   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Direct Laser Sintering of Ceramics [PDF]

open access: yes, 2003
For more than one decade layer manufacturing technologies assist the development of new products. Due to a layer-wise build-up of a three-dimensional geometry, nearly every complex design is producible in a short period of time.
Ader, Christoph, Klocke, F.
core   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Survey on Additive Manufacturing, Cloud 3D Printing and Services

open access: yes, 2017
Cloud Manufacturing (CM) is the concept of using manufacturing resources in a service oriented way over the Internet. Recent developments in Additive Manufacturing (AM) are making it possible to utilise resources ad-hoc as replacement for traditional ...
Baumann, Felix W., Roller, Dieter
core   +1 more source

A method to Formalise the Rapid Prototyping Process [PDF]

open access: yes, 1999
Facing the increasing complexity of the product design area, (reduction of cycle times, introduction of simultaneous engineering, introduction of digital mock-up, ... ) a research department which wants to define a rapid prototyping process is confronted
AOUSSAT, Améziane   +2 more
core   +6 more sources

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