Results 81 to 90 of about 1,789,575 (241)

Potential of New Sustainable Green Geopolymer Metal Composite (GGMC) Material as Mould Insert for Rapid Tooling (RT) in Injection Moulding Process. [PDF]

Materials (Basel), 2023
Yin ATM, Rahim SZA, Al Bakri Abdullah MM, Nabialek M, Abdellah AE, Rennie A, Tahir MFM, Titu AM.   +7 more
europepmc   +1 more source

Prospecting the protein design landscape

FEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona, Katharina T. Stonig, Jens Meiler, Clara T. Schoeder, Monica L. Fernández‐Quintero   +4 more
wiley   +1 more source

Topology Optimization of Polymer-Based Bending Tools Manufactured via Additive Technology: Numerical and Experimental Validation

Journal of Manufacturing and Materials Processing
Sheet metal forming is a widely used manufacturing process, but the high cost and long production time of traditional forming tools limit its flexibility, especially for prototyping and small-batch production.
Luca Giorleo, Kudret Irem Deniz
doaj   +1 more source

Artificial molecular machines and motors—Design and control of nanoscale motion

FEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

Process Analysis for Rapid Tooling Technology Based on Rapid Prototyping

, 2011
This paper discussed the working principle, classification, modeling process and technology features for rapid tooling based on rapid prototyping and investigated into the difference between rapid tooling with traditional modeling manufacture.
Jun Su, Hong Pu Liu, Xiao Jing Li
core   +1 more source

Integrated rapid prototyping and tooling [PDF]

, 2011
The integration of rapid prototyping and rapid tooling is being used for getting product to the market quickly by resolving along-standing conflict between design and manufacturing.
Bocevska, Andrijana
core   +2 more sources

Smaller is better: nanobodies meet NMR

FEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Influência dos parâmetros de moldagem na estrutura e propriedade de peças de paredes espessas e finas de polipropileno isotático injetadas em moldes-protótipo fabricados por vazamento de resina epóxi [PDF]

, 2007
Tese (doutorado) - Universidade Federal de Santa Catarina, Centro Tecnologico. Programa de Pós-Graduação em Engenharia MecânicaA necessidade de protótipos com as mesmas propriedades do produto final, fez com que as técnicas de prototipagem rápida ...
Cavalheiro, Andrei Zwetsch
core