Results 101 to 110 of about 1,789,575 (241)

The new helicopter composite duct manufacturing technology

open access: yesHangkong gongcheng jinzhan
In order to realize the high-quality,low-cost,agile and rapid manufacturing of AC332 civil helicopter composite duct structure,a new helicopter composite duct manufacturing technology is put forward by carrying out forward process design according to ...
QI Shutao
doaj   +1 more source

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

open access: yesMolecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth   +17 more
wiley   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim   +17 more
wiley   +1 more source

Rapid casting and new technologies in investment casting

open access: yesIngeniería e Investigación, 2006
Rapid prototyping is a manufacturing process which is different to traditional methods as material is not removed or formed but added to obtain the designed pieces.
Claudia Marcela Sánchez R   +1 more
doaj  

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

open access: yesFEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj   +3 more
wiley   +1 more source

Rapid Electroforming Tooling

open access: yes, 2000
A method of rapid electroforming tooling for the production of metal tools including molds, dies, and electrical discharge machining electrodes is developed.
Bo Yang   +3 more
core   +2 more sources

Rapid precision casting for complex thin-walled aluminum alloy parts [PDF]

open access: yesChina Foundry, 2004
Based on Vacuum Differential Pressure Casting (VDPC) precision forming technology and the Selective Laser Sintering (SLS) Rapid Prototyping (RP) technology, a rapid manufacturing method called Rapid Precision Casting (RPC) process from computer three ...
Xuanpu DONG, Naiyu HUANG, Zitian FAN
doaj  

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

open access: yesFEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee   +3 more
wiley   +1 more source

The development and use of strategic business performance improvement frameworks for rapid prototyping and tooling : executive summary [PDF]

open access: yes
Increasing global competition within industry has forced businesses to respond by reducing costs and product development lead times in order to survive.
Halliday, Ian
core  

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