Results 71 to 80 of about 1,789,575 (241)

Rapid Tooling for Zinc Spin Casting using Arc Metal Spray Technology [PDF]

open access: yes, 2004
A research and development effort was made to investigate the feasibility of rapid tooling for zinc spin casting using stereolithography (SL) and arc metal spray technologies.
Hermanto, H.   +6 more
core   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Analysis of the Geometric Accuracy of Wax Models Produced Using PolyJet Molds

open access: yesTehnički Glasnik
The article presents an analysis of the geometric accuracy of wax models produced using PolyJet molds. Photopolymer resin was used to make the molds, and the surface of the model was finished in a gloss mode in the 3D printing process. This allows you to
Mariusz Cygnar   +6 more
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

open access: yesFEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança   +2 more
wiley   +1 more source

Rapid Tooling mit Stereolithographie

open access: yes, 2006
Vor etwa drei Jahren wurden Komposit-Kunstharze für die Stereolithographie (SL) auf dem Markt eingeführt. Sie bieten Leistungsmerkmale, die jenseits dessen liegen, was traditionelle SL-Kunstharze auszeichnet. Insbesondere die hohe Wärmeformbeständigkeit
Montgomery, Eva
core  

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Rapid Tooling for Microinjection Moulding of Proof-of-Concept Microfluidic Device: Resin Insert Capability and Preliminary Validation

open access: yesApplied Sciences
Producing sustainable microfluidic devices on a large scale has become a trend in the biomedical field. However, the transition from laboratory prototyping to large-scale industrial production poses several challenges due to the gap between academia and ...
Benedetta Stampone   +7 more
doaj   +1 more source

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