Results 1 to 10 of about 126 (62)

Clinical, serological and DNA testing in Bengo Province, Angola further reveals low filarial endemicity and opportunities for disease elimination [PDF]

Parasite Epidemiology and Control, 2020
The prevalence of Loa loa, Onchocerca volvulus and Wuchereria bancrofti infections in an under-surveyed area of Bengo Province, Angola, was determined by surveying 22 communities with a combination of clinical, serological and DNA diagnostics. Additional
Thomas R Unnasch, Miguel Brito, Louise Kelly-Hope   +2 more
exaly   +4 more sources

Loa loa and Mansonella perstans microfilaremia in the department of Lékoumou, Republic of Congo [PDF]

Parasites and Vectors, 2023
Background Loiasis is endemic in the northern and western part of the Republic of Congo. Between 2004 and 2010, surveys were conducted, using the RAPLOA method, in all departments of the Republic of Congo to assess the distribution of loiasis.
Michel Boussinesq, Jérémy T Campillo, Cédric B Chesnais   +2 more
exaly   +3 more sources

Validation of the rapid assessment procedure for loiasis (RAPLOA) in the democratic republic of Congo [PDF]

Parasites and Vectors, 2012
Background A simple method called RAPLOA, to rapidly assess what proportion of people in a community are infected with L. loa and hence which communities are at high risk of severe adverse reactions following ivermectin treatment, was developed in ...
Samuel Wanji, Peter Diggle, Floribert Tepage   +2 more
exaly   +4 more sources

The Geographic Distribution of Loa loa in Africa: Results of Large-Scale Implementation of the Rapid Assessment Procedure for Loiasis (RAPLOA) [PDF]

PLoS Neglected Tropical Diseases, 2011
BackgroundLoiasis is a major obstacle to ivermectin treatment for onchocerciasis control and lymphatic filariasis elimination in central Africa. In communities with a high level of loiasis endemicity, there is a significant risk of severe adverse ...
Samuel Wanji, Peter Diggle, Mounkaila Noma   +2 more
exaly   +4 more sources

Integrated risk mapping and landscape characterisation of lymphatic filariasis and loiasis in South West Nigeria [PDF]

Parasite Epidemiology and Control, 2018
Nigeria has the heaviest burden of lymphatic filariasis (LF) in sub-Saharan Africa, which is caused by the parasite Wuchereria bancrofti and transmitted by Anopheles mosquitoes. LF is targeted for elimination and the national programme is scaling up mass
David Molyneux, Michelle C Stanton, Louise Kelly-Hope   +2 more
exaly   +4 more sources

Analysis of diagnostic test outcomes in a large loiasis cohort from an endemic region: Serological tests are often false negative in hyper-microfilaremic infections. [PDF]

PLoS Neglected Tropical Diseases
BackgroundThe parasitic disease loiasis is associated with significant morbidity and mortality. Individuals with hyper-microfilaremia (greater than 20,000 microfilariae per mL of blood) may suffer from serious treatment-related or spontaneous adverse ...
Luzia Veletzky, Kirsten Alexandra Eberhardt, Jennifer Hergeth, Daniel Robert Stelzl, Rella Zoleko Manego, Ruth Kreuzmair, Gerrit Burger, Johannes Mischlinger, Matthew B B McCall, Ghyslain Mombo-Ngoma, Ayôla Akim Adegnika, Selidji Todagbe Agnandji, Pierre Blaise Matsiegui, Bertrand Lell, Peter Kremsner, Benjamin Mordmüller, Dennis Tappe, Michael Ramharter   +17 more
doaj   +2 more sources

Rapid integrated clinical survey to determine prevalence and co-distribution patterns of lymphatic filariasis and onchocerciasis in a Loa loa co-endemic area: The Angolan experience [PDF]

Parasite Epidemiology and Control, 2017
The Republic of Angola is a priority country for onchocerciasis and lymphatic filariasis (LF) elimination, however, the co-distribution of the filarial parasite Loa loa (loiasis) is a significant impediment, due to the risk of severe adverse events (SAEs)
Miguel Brito, Rossely Paulo, Pedro Van-Dunem, António Martins, Thomas R. Unnasch, Robert J. Novak, Benjamin Jacob, Michelle C. Stanton, David H. Molyneux, Louise A. Kelly-Hope   +9 more
doaj   +2 more sources

Co-endemicity of loiasis and onchocerciasis in rain forest communities in southwestern Nigeria. [PDF]

PLoS Neglected Tropical Diseases, 2015
BackgroundLoiasis is currently receiving attention as a disease of public health importance because of the possibility of increased risk of developing neurologic serious adverse event following mass ivermectin treatment against onchocerciasis in ...
Olusola Ojurongbe, Akeem Abiodun Akindele, Monsuru Adebayo Adeleke, Matthew Oyebode Oyedeji, Samuel Adeyinka Adedokun, Josephine Folashade Ojo, Callistus Adewale Akinleye, Oloyede Samuel Bolaji, Olusegun Adelowo Adefioye, Oluwaseyi Adegboyega Adeyeba   +9 more
doaj   +2 more sources

Innovative tools for assessing risks for severe adverse events in areas of overlapping Loa loa and other filarial distributions: the application of micro-stratification mapping [PDF]

Parasites & Vectors, 2014
Background The wide distribution of Loa loa infection (loiasis) throughout the Democratic Republic of Congo (DRC) is a major obstacle to the plans to eliminate onchocerciasis and lymphatic filariasis (LF) because the standard drug regime is dependent on ...
Louise A Kelly-Hope, Jorge Cano, Michelle C Stanton, Moses J Bockarie, David H Molyneux   +4 more
doaj   +2 more sources

Rapid assessment of Loa loa prevalence and its implications on onchocerciasis and lymphatic filariasis elimination programmes in Osun state, Nigeria

Discover Public Health
Loiasis remains a significant public health concern, particularly in regions co-endemic for onchocerciasis and lymphatic filariasis, where high Loa loa microfilaraemia increases the risk of Severe Adverse Events (SAE) following mass drug administration ...
Q. O. Adeshina, A. M. Rufai, O. G. Dauda, L. O. Busari, D. I. Azeez, Z. O. Iwalewa, O. O. Abuh, G. B. Jokanola, A. A. Ayannibi, M. M. Abdulsalam, Y. O. Yusuff, G. O. Ige, L. O. Adegoke, O. A. Surakat, K. A. Fasasi, M. A. Adeleke   +15 more
doaj   +1 more source