Results 141 to 150 of about 93,184 (344)
The FEBS Journal, EarlyView.FPR2 activation mediates NOX‐dependent LAT1 expression and, in turn, promotes mTORC1 signaling. Upon stimulation with WKYMVm, the FPR2‐NOX2‐ROS axis upregulates LAT1 via increased c‐Myc phosphorylation and decreased miR‐126. Additionally, it promotes CD98 translocation to the plasma membrane.
Myrhiam Cassese +5 more
wiley +1 more source
From Disease Control to Disease Modification: The Atopic Dermatitis Disease Activity Index
Allergy, EarlyView.
Thomas Bieber +3 more
wiley +1 more source
Ibis, EarlyView.Biodiversity conservation requires effective monitoring of ecological communities in remote locations, where limited accessibility often restricts survey efforts. Passive acoustic monitoring (PAM) is becoming an established method for measuring biodiversity, facilitated by the increased accessibility of autonomous recording units.
Vikram Malhi +6 more
wiley +1 more source
Ibis, EarlyView.The identification of key habitats of threatened species and of extrinsic environmental factors that influence their resilience to human‐induced environmental changes are the foundation for the definition of conservation objectives. Using the presence and numerical abundance data collected in a long‐term survey (2000–24) of breeding colonies of Lesser ...
Maurizio Sarà, Rosario Mascara
wiley +1 more source
Tui Na Acupressure Modulates Treg Immunosuppression via FoxP3/mTORC1 Signalling in ALS Mice
Immunology, EarlyView.The proposed mechanism by which Tui Na acupressure improves motor and cognitive dysfunction in ALS mice by activating the FoxP3/mTORC1 pathway. ABSTRACT Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease driven by neuroinflammation, where regulatory T cell (Treg) dysfunction exacerbates immune imbalance.
Jie Han +7 more
wiley +1 more source
Safety and efficacy of nemolizumab for atopic dermatitis up to 2 years in open‐label extension study
Journal of the European Academy of Dermatology and Venereology, EarlyView.This study evaluated long‐term safety and efficacy in patients with moderate‐to‐severe atopic dermatitis. Patients with and without previous nemolizumab experience received nemolizumab 30 mg Q4W plus TCS/TCI. Nemolizumab was well‐tolerated through 104 weeks with clinically meaningful improvements in disease signs and symptoms.
Matthias Augustin +24 more
wiley +1 more source
Habitat-Dependent Provisioning Patterns Are Modulated by Weather Conditions in a Rapidly Declining Farmland Raptor. [PDF]
Ecol EvolWe monitored parental food provisioning of Little Owls in four European countries with contrasting farmland structure using nestbox cameras and demonstrated that across all countries, provisioning rate and biomass increased with the area of high‐quality habitats.
Sailas SS +6 more
europepmc +2 more sources
The SWITCH algorithm: An expert consensus on treat‐to‐target criteria for chronic prurigo
Journal of the European Academy of Dermatology and Venereology, EarlyView.The SWITCH project assessed patients' most distressing symptoms and therapy goals, followed by an expert‐based consensus procedure to define T2T criteria for patients with chronic prurigo (CPG)/prurigo nodularis. Based on these validated criteria, a 4‐step SWITCH algorithm was established to enhance CPG therapy outcomes and reduce patient burden ...
Lea S. Stahl +16 more
wiley +1 more source