Results 51 to 60 of about 21,750 (299)

The mTORC1/S6K/PDCD4/eIF4A Axis Determines Outcome of Mitotic Arrest

open access: yesCell Reports, 2020
Summary: mTOR is a serine/threonine kinase and a master regulator of cell growth and proliferation. Raptor, a scaffolding protein that recruits substrates to mTOR complex 1 (mTORC1), is known to be phosphorylated during mitosis, but the significance of ...
Mohamed Moustafa-Kamal   +8 more
doaj   +1 more source

A Systematic Review of Substance Misuse Treatment Processes and Outcomes as Implemented in Prisons for Men in the UK

open access: yesCriminal Behaviour and Mental Health, EarlyView.
ABSTRACT Background With a rising prison population, a substantial portion of whom are identified as substance misusers, it is important to understand the availability of treatment pathways, their successes and areas for improvement. Given the likely importance of national factors in criminal justice and substance use service provision, we chose to ...
Kim Barnett   +9 more
wiley   +1 more source

Non‐Passerine Birds in Zoos: A Global Approach on Distribution Patterns of Threatened Birds in Zoological Institutions 动物园中非雀形目鸟类:全球动物机构中受威胁鸟类的分布模式研究

open access: yesIntegrative Conservation, EarlyView.
Only 1541 (34.2%) of 4503 recognized non‐passerine bird species are held in ZIMS institutions worldwide. Approximately ~83% of the species kept globally are classified as non‐threatened and ~16% as threatened. To improve the conservation of threatened birds, a shift toward keeping threatened species should be considered within ex situ management ...
Anna Wahle   +6 more
wiley   +1 more source

Safety of Baricitinib for the Treatment of Atopic Dermatitis in Adults Over a Median of 1.6 and up to 4.6 Years Treatment: Final Integrated Analysis of Eight Clinical Trials

open access: yesJEADV Clinical Practice, EarlyView.
ABSTRACT Background Baricitinib is a selective Janus kinase (JAK)1/JAK2 inhibitor approved in more than 70 countries for the treatment of moderate‐to‐severe atopic dermatitis (AD) in adults, and in over 30 countries for adolescents and children from age 2 years with moderate‐to‐severe AD, who are candidates for systemic therapy.
Antonio Costanzo   +11 more
wiley   +1 more source

The Steppe Eagle Global Conservation Status Was Raised

open access: yesПернатые хищники и их охрана, 2015
An announcement which gives the current status of the steppe eagle in European Red List and IUCN Red List and reviews its status change in Russia and Kazakhstan.
Igor V. Karyakin
doaj   +1 more source

Transcriptional Regulation of NK Cell Development by mTOR Complexes

open access: yesFrontiers in Cell and Developmental Biology, 2020
The mechanistic target of Rapamycin (mTOR) is essential for multiple cellular processes. The unique roles of mTOR complex 1 (mTORC1) or mTOR2 in regulating immune functions are emerging.
Chao Yang   +5 more
doaj   +1 more source

Decline of a Raptor [PDF]

open access: yesNature, 1969
Peregrine Falcon Populations Their Biology and Decline. Edited by Joseph J. Hickey. (Proceedings of an International Conference sponsored by the University of Wisconsin.) Pp. xxii + 596 + 59 plates. (University of Wisconsin Press: Madison and London, February 1969.) $10; 95s.
openaire   +2 more sources

Characteristics of Adult Patients With Atopic Dermatitis Initiating Biologics and Janus Kinase Inhibitors in the CorEvitas Atopic Dermatitis Registry

open access: yesJEADV Clinical Practice, EarlyView.
ABSTRACT Background Biologics and Janus kinase inhibitors (JAKi) are two advanced systemic treatment options for patients with atopic dermatitis (AD). The decision to initiate one of these therapies is complex and may be driven by many factors.
Eric L. Simpson   +12 more
wiley   +1 more source

Monitoring Results of the Eagle Owl Population in the Strip-shaped Pine Forests in the Altai Kray, Russia

open access: yesПернатые хищники и их охрана, 2015
Based on author’s research in 2013–2014 the paper contains information on distribution, numbers and breeding biology of the Eagle Owl (Bubo bubo) in the strip-shaped pine forests in the Altai Kray. A total of 146 breeding territories of the Eagle Owl (61.
Igor V. Karyakin
doaj   +1 more source

Scavenger dynamics at cervid carcasses in a chronic wasting disease endemic zone

open access: yesThe Journal of Wildlife Management, EarlyView.
This study quantifies scavenger species use of 20 deer carcasses in a chronic wasting disease endemic zone, including species‐specific time spent on carcasses and carcass materials consumed. We discuss the implications of our results for scavengers' roles in potential disease transmission dynamics.
Kelly C. Bye   +2 more
wiley   +1 more source

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