Results 11 to 20 of about 1,107,549 (295)

Molecular red cell genotyping of rare blood donors in South Africa to enhance rare donor-patient blood matching

open access: yesAfrican Journal of Laboratory Medicine, 2021
Background: Molecular red cell genotyping is devoid of serology limitations such as the scarcity of rare antisera and the possibility of inconclusive results due to biological interferences.
Lavendri Govender   +3 more
doaj   +1 more source

GapClust is a light-weight approach distinguishing rare cells from voluminous single cell expression profiles

open access: yesNature Communications, 2021
While rare cell type identification is indispensable in single cell studies, powerful tools with high detection accuracy and computational efficiency are still lacking.
Botao Fa   +7 more
doaj   +1 more source

The Blood Circulating Rare Cell Population. What is it and What is it Good For?

open access: yesCells, 2020
Blood contains a diverse cell population of low concentration hematopoietic as well as non-hematopoietic cells. The majority of such rare cells may be bone marrow-derived progenitor and stem cells. This paucity of circulating rare cells, in particular in
Stefan Schreier, Wannapong Triampo
doaj   +1 more source

Evaluation of Cell Type Annotation R Packages on Single-cell RNA-seq Data

open access: yesGenomics, Proteomics & Bioinformatics, 2021
Annotating cell types is a critical step in single-cell RNA sequencing (scRNA-seq) data analysis. Some supervised or semi-supervised classification methods have recently emerged to enable automated cell type identification.
Qianhui Huang   +3 more
doaj   +1 more source

DigiTAG–a RNA Sequencing Approach to Analyze Transcriptomes of Rare Cell Populations in Drosophila melanogaster

open access: yesBio-Protocol, 2020
Cell-type specific transcriptional programs underlie the development and maintenance of organs. Not only distinct cell types within a tissue, even cells with supposedly identical cell fates show a high degree of transcriptional heterogeneity. Inevitable,
Lisa Landskron   +3 more
doaj   +1 more source

ProgClust: A progressive clustering method to identify cell populations

open access: yesFrontiers in Genetics, 2023
Identifying different types of cells in scRNA-seq data is a critical task in single-cell data analysis. In this paper, we propose a method called ProgClust for the decomposition of cell populations and detection of rare cells.
Han Li   +10 more
doaj   +1 more source

Clump sequencing exposes the spatial expression programs of intestinal secretory cells

open access: yesNature Communications, 2021
Combining scRNA-seq with spatial information to enable the reconstruction of spatially-resolved cell atlases is challenging for rare cell types. Here the authors present ClumpSeq, an approach for sequencing small clumps of tissue attached cells, and ...
Rita Manco   +5 more
doaj   +1 more source

Comprehensive multi-omics single-cell data integration reveals greater heterogeneity in the human immune system

open access: yesiScience, 2022
Summary: Single-cell transcriptomics enables the definition of diverse human immune cell types across multiple tissues and disease contexts. Further deeper biological understanding requires comprehensive integration of multiple single-cell omics ...
Congmin Xu   +5 more
doaj   +1 more source

Transcriptional landscape of epithelial and immune cell populations revealed through FACS-seq of healthy human skin. [PDF]

open access: yes, 2017
Human skin consists of multiple cell types, including epithelial, immune, and stromal cells. Transcriptomic analyses have previously been performed from bulk skin samples or from epithelial and immune cells expanded in cell culture.
Ahn, Richard S   +9 more
core   +1 more source

Myoepithelial carcinoma of mixed cell type: a rare entity [PDF]

open access: yesJournal of Dermatology & Cosmetology, 2018
Myoepitheliomas represent a large group of uncommon mesenchymal neoplasms characterized by myoepithelial differentiation.
Erica Dalla Venezia   +8 more
openaire   +1 more source

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