Results 91 to 100 of about 493,260 (275)

CX3CL1 in Early Detection of Alzheimer's Disease: Plasma Dynamics Across Age and Disease Stages

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Backgrounds Alzheimer's disease (AD) is characterized by amyloid‐beta plaques, tau tangles, and neuroinflammation. C‐X3‐C motif chemokine ligand 1 (CX3CL1, also known as fractalkine), a neuroimmune chemokine implicated in AD pathogenesis, shows inconsistent alterations in plasma/serum across studies.
Ling Wang, Yujie Liu, Fei Li, Xuelin Li, Lanlan Li, Jie Zhang, Yali Xu   +6 more
wiley   +1 more source

Developmental and Epileptic Encephalopathy due to Biallelic Pathogenic Variants in PIGM

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective PIGM encodes a critical enzyme in the glycosylphosphatidylinositol (GPI)‐anchor biosynthesis pathway. While promoter‐region mutations in PIGM have been associated with a relatively mild phenotype characterized by portal vein thrombosis and absence seizures, recent evidence suggests that coding‐region mutations result in a more severe
Júlia Sala‐Coromina, Anna Marcé‐Grau, Barbara Masotto, Marta Codina, Lamia BenJemaa, Yasmina Elaribi, Mónica Martinez‐Gallo, Roger Colobran, Angel Sanchez‐Montañez, Irene Valenzuela, Yoshiko Murakami, Alfons Macaya   +11 more
wiley   +1 more source

Exposure risk assessment of rare earth element in vegetables from typical rare earth mining areas across four provinces in China

Zhongguo shipin weisheng zazhi
ObjectiveTo investigate the distribution patterns and population exposure risks of rare earth elements （REEs） in vegetables from typical rare earth mining areas across four provincial-level administrative divisions in China （Guangdong， Guangxi， Shandong，
LIU Hang, SONG Yan, JIANG Dingguo, YONG Ling, SUI Haixia, LI Jianwen, MAO Weifeng, WANG Yin   +7 more
doaj   +1 more source

Rare Earth Abundances in Meteoritic Chondrules [PDF]

Rare earth elements abundance in meteoritic chondrites determined by radiochemical neutron activation ...
Olehy, D. A., Schmitt, R. A., Smith, R. H.   +2 more
core   +1 more source

Ketogenic Diet as an Epigenetic Therapy in SETD1B‐Related Epilepsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Histone lysine methyltransferases such as SETD1B regulate chromatin structure and gene transcription. Ketone bodies, including butyrate, act as histone deacetylase inhibitors. We report a 4‐year‐old boy with SETD1B‐related absence epilepsy, refractory to conventional medications, who achieved sustained > 90% seizure reduction on the Modified ...
Erica Tsang, Brian S. Gloss, Jessica P. Hayes, Andrew J. A. Holland, Manoj P. Menezes, Joceline A. Branson, Shekeeb S. Mohammad, Jingya J. Yan, Shrujna Patel, Velda X. Han, Russell C. Dale   +10 more
wiley   +1 more source

Low Incidence of Relapses After Vaccination in Anti‐Aquaporin‐4 Antibody‐Positive NMOSD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Patients with neuromyelitis optica spectrum disorder (NMOSD) may experience increased signs and symptoms of their underlying disease when vaccinated against meningococcal disease before receiving complement component 5 inhibitor therapies. This retrospective analysis indicated an overall low relapse incidence (mean [range], 3.3% [0.7%–10.6 ...
Sean J. Pittock, Jin Nakahara, Becky Parks, Kerstin Allen, Sami Fam   +4 more
wiley   +1 more source

Rare Earth Elements

, 2021
This is the author accepted manuscript. The final version is available from Elsevier via the DOI in this record ; The rare earth elements (REE) consist of 17 elements Sc, Y and the lanthanoids La – Lu. Their magnetic and luminescent properties make them essential components of digital and low carbon technologies.
openaire   +2 more sources

A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling, Mark D. Parker, Sven Kerst, Richard A. Pasternack, Jacob Tondreau, Marjolein Breur, Gemma M. van Rooijen‐van Leeuwen, Davide Tonduti, Ettore Salsano, Alejandra Darling, Joanna A. E. van Wijk, Susanna Törnroth‐Horsefield, Marianna Bugiani, Petra J. W. Pouwels, Quinten Waisfisz, Marjo S. van der Knaap, Rogier Min   +16 more
wiley   +1 more source

Research Progress on Leaching of Rare Earth Elements in Phosphogypsum

Medžiagotyra
With the increasing global demand for rare earth elements and the depletion of traditional mineral resources, recycling rare earth elements from industrial solid waste has become an important direction of sustainable resource utilization.
Jing TAN, Guodong LI, Dahai YOU, Jin ZHANG, Chaohong ZHANG, Xinghua PENG, Li ZHANG, Xiuquan HU   +7 more
doaj   +1 more source

The Mountain Pass Rare-Earth Deposits [PDF]

, 1954
Rare-earth minerals were discovered near Mountain Pass in northeastern San Bernardino County, Calif., in April 1949, and in the following year the Sulphide Queen carbonate body was found.
Olson, J. C., Pray, L. C.
core