Results 61 to 70 of about 490,516 (296)

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Synthesis, Crystal Structure and Optical Properties of Novel 1,10-Phenanthroline Derivatives Containing 2,6-Diisopropylphenoxy Substituents

Crystals
Two phenanthroline derivatives, 2-(2,6-diisopropylphenoxy)-9-phenyl-1,10-phenanthroline and 2,9-bis(2,6-diisopropylphenoxy)-1,10-phenanthroline, were synthesized. The unsymmetrical derivative was obtained in high yield through a sequence combining Suzuki
Martin Tsvetkov, Rumen Lyapchev, Mihail Kolarski, Bernd Morgenstern, Joana Zaharieva   +4 more
doaj   +1 more source

Comment on: “Challenging the Odds: Long‐Term Survival in Pediatric Diffuse Midline Glioma With H3 K27M and BRAF V600 Co‐Mutations Treated With Upfront Radiotherapy and Targeted Therapy”

Pediatric Blood &Cancer, EarlyView.
Natália Dassi, Andrea Maria Cappellano
wiley   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Effect of Rare Earth Content on Microstructure and Corrosion Resistance of HRB400 Steel [PDF]

Teshugang
The steel rebar with low cost and excellent corrosion resistance were prepared by adding trace lanthanum （La） and cerium （Ce） rare earth elements. The effect of rare earth addition on the microstructure and corrosion resistance of corrosion resistant ...
Chen　Hao, Sun　Yibin, Xie　Qingmin, Liu　Xiaolong, Zhang　Cunshuai, Peng　Zhixian, Cheng　Zhaoyang, Liu　Jing
doaj   +3 more sources

Mineralogía y geoquímica de tierras raras en el Cinturón Pirítico Español [PDF]

, 1992
Three volcanogenic massive sulphide deposits of the Iberian Pyrite Belt are considered. Masa Valverde, Aguas Tefiidas and LomeroPoyatos. By means of the mineralogy and the geochemistry distributions of the rare earth elements (REE), three typologies of ...
Espí Rodríguez, José Antonio, Ruíz García, Casilda   +1 more
core   +1 more source

Standard model of the rare-earths, analyzed from the Hubbard I approximation [PDF]

, 2016
In this work we examine critically the electronic structure of the rare-earth elements by use of the so-called Hubbard I approximation. From the theoretical side all measured features of both occupied and unoccupied states are reproduced, without ...
Bergman, A., Bergqvist, L., Delin, A., Di Marco, I., Eriksson, O., Johansson, B., Katsnelson, M. I., Klautau, A. B., Kvashnin, Y. O., Lichtenstein, A. I., Locht, I. L. M., Pereiro, M., Rodrigues, D. C. M.   +12 more
core   +2 more sources

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Effect of Rare Earth Cerium and Yttrium on the High Temperature Oxidation Resistance of Austenitic Heat-resistant Steel [PDF]

Teshugang
The addition of trace rare earth elements can significantly enhance the oxidation resistance of alloys， but the action mechanisms of different rare earth elements vary and have not been widely understood.
Du　Xiaojian, Li Taotao, Zhou Diaoyu
doaj   +3 more sources

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source