Results 161 to 170 of about 9,600,367 (343)

Evolution‐guided yeast complementation reveals functional differences in human PSPH variants

FEBS Open Bio, EarlyView.
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez, Diana Ascencio, Miguel Vallebueno‐Estrada, Eduardo González‐Orozco, Christian Eduardo Martínez‐Guerrero, Rafael Montiel, Alexander DeLuna   +6 more
wiley   +1 more source

Government Documents on Rare Earth Minerals [PDF]

, 2012
Rare earth minerals contain unique chemical and physical properties such as lanthanum, are found in small concentrations, need extensive precise processes to separate, and are critical components of modern technologies such as laser guidance systems ...
Chapman, Bert
core   +1 more source

Call for Papers: Rare Books Collections in Brazil: the founding collections and collection development policies

, 2016
The National Library of Brazil and the National Rare Books Program Identification (Plano Nacional de Recuperação de Obras Raras), has announced the call for papers to the 12th National Meeting of Rare Books to be held 24th and 25th November 2016.
IFLA Rare Books & Special Collections Section
core  

In silico and in vitro exploration of a tyrosinase for biocatalytic production of catechols

FEBS Open Bio, EarlyView.
Tyrosinase from Ralstonia pseudosolanacearum is a promising biocatalyst for producing valuable catechols from monophenol substrates. This tyrosinase is uniquely suited to this due to its high monophenolase : diphenolase ratio. We combined in silico docking and in vivo kinetic characterisation of this tyrosinase with 11 industrially relevant monophenols,
James Britton, Fang Zhao, Reeta Davis, Meg Walsh, Kevin E O'Connor, David O'Connell, Tanja Narancic   +6 more
wiley   +1 more source

Report from the CILIP Rare Books and Special Collections Group annual conference, 2017

, 2017
The Rare Books and Special Collections Group Conference 2017, hosted at the picturesque University of Sussex, had ‘Collections at Risk’ as its theme. Over the course of the three-day conference we heard talks from people working in a variety of roles who
IFLA Rare Books & Special Collections Section
core  

From patient advocacy to patient‐driven research: Building active partnerships beginning at the bench to reach the bedside

FEBS Open Bio, EarlyView.
Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia, Rachel Heilmann, Maximiliano Barrientos, Laura MacNeill, Ingrid Vallee, Sarah K. Schultz, Patrick O'Donoghue, Angelica A. Moresco, Victoria M. Siu, Ilka U. Heinemann   +9 more
wiley   +1 more source

Flora of the Yelanetsky Steppe Nature Reserve, Mykolaiv Oblast, Ukraine: a diversity and structural analysis

Environmental & Socio-economic Studies
The aim of the study is to inventory the current composition of the flora of the Yelanetsky Steppe Nature Reserve, Mykolaiv Oblast, Ukraine, to analyze its structure for the first time, and to characterize the role of the reserve in conserving the ...
Drabyniuk Galyna V., Shynder Oleksandr I., Kolomiychuk Vitalii P., Konaikova Valeriia O.   +3 more
doaj   +1 more source

Cytotoxic Activity of Thirteen Endemic and Rare Plants from Chaharmahal and Bakhtiari Province in Iran. [PDF]

Iran J Pharm Res, 2019
Emami SA, Kheshami S, Ramazani E, Akaberi M, Iranshahy M, Kazemi SM, Tayarani-Najaran Z.   +6 more
europepmc   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

Genetic dissection of human ABCE1 in yeast reveals separable requirements for ribosome recycling and suppression of aberrant reinitiation

FEBS Open Bio, EarlyView.
Human ABCE1 cannot functionally replace its yeast ortholog. Yeast–human chimera analysis identified NBD1 as a major interspecies barrier. Genetic screening yielded hABCE1 revertants that rescue yeast viability but fail to suppress aberrant translation reinitiation in the 3′ UTR.
Eriko Nakata, Yuxin Li, Kei Endo, Koichi Ito   +3 more
wiley   +1 more source