AI Guided Protein Design for Next‐Generation Autogenic Engineered Living Materials
Advanced Intelligent Systems, EarlyView.Autogenic engineered living materials (ELMs) integrate biology and materials science to create self‐regenerating and self‐healing materials. This perspective highlights emerging strategies in protein engineering and AI‐guided de novo design to expand the capabilities of autogenic ELMs.
Hoda M. Hammad, Anna M. Duraj‐Thatte
wiley +1 more source
American Journal of Medical Genetics Part A, EarlyView.ABSTRACT Cytosolic phosphoenoylpyruvate carboxykinase (PEPCK‐C) is an essential, rate‐limiting enzyme in the gluconeogenesis pathway. PEPCK‐C deficiency presents with hypoglycaemia, hyperlactataemia and hepatopathy, and was first reported in association with bi‐allelic PCK1 variants in 2014.
Isaac Bernhardt +9 more
wiley +1 more source
Mass Spectrometry Approach for Differentiation of Positional Isomers of Saccharides: Toward Direct Analysis of Rare Sugars. [PDF]
Anal Chem, 2023 Amoah E +4 more
europepmc +1 more source
Understanding Neurodegenerative Diseases From the −Omics Perspective: Lessons Learnt
Annals of Neurology, EarlyView.As the population ages, certain neurodegenerative diseases (NDs) are becoming a major health issue. For this reason, this review will focus on the most common ND with onset after 65 years old; Alzheimer's disease, Parkinson's disease, Lewy body dementia, and frontotemporal dementia.
Laura Ibanez +5 more
wiley +1 more source
Microbial Cell FactoriesBackground D-psicose, a rare sugar with significant health benefits, holds great promise as a low-calorie sweetener. Its synthesis requires the enzyme called D-psicose 3-epimerase (DPEase), which converts D-fructose into D-psicose.
Pimsiriya Srila +3 more
doaj +1 more source
Rare sugars: metabolic impacts and mechanisms of action: a scoping review. [PDF]
Br J Nutr, 2022 Smith A +7 more
europepmc +1 more source
Metabolism and Health Effects of Rare Sugars in a CACO-2/HepG2 Coculture Model. [PDF]
Nutrients, 2022 van Laar A +6 more
europepmc +1 more source
Tackling food marketing to children in a digital world: trans-disciplinary perspectives. Children’s rights, evidence of impact, methodological challenges, regulatory options and policy implications for the WHO European Region [PDF]
, 2016 There is unequivocal evidence that childhood obesity is influenced by marketing of foods and non-alcoholic beverages high in saturated fat, salt and/or free sugars (HFSS), and a core recommendation of the WHO Commission on Ending Childhood Obesity is to ...
Boyland, Emma +6 more
core
Self‐Assembled (Aza)BODIPY Dyes for Biomedical in Vivo Imaging
Angewandte Chemie International Edition, EarlyView.This minireview classifies (aza)BODIPY dyes according to their molecular stacking modes and aggregate types (H‐, oblique‐, or J‐type) in aqueous media, correlating these features with their multimodal imaging performance. By linking molecular design, exciton coupling, and pathway‐dependent assembly, we provide a framework for engineering next ...
Antonia Albers +2 more
wiley +1 more source
[Simultaneous determination of six rare sugars in solid foods by high performance liquid chromatography-evaporative light-scattering detection]. [PDF]
Se Pu, 2023 Liu Y +9 more
europepmc +1 more source