Results 1 to 10 of about 1,462 (194)

Unveiling the impact of allulose on oral microbiota and biofilm formation via a cariogenic potential assessment platform [PDF]

Frontiers in Cellular and Infection Microbiology
IntroductionThe increased consumption of refined carbohydrates, particularly sucrose, has contributed to metabolic disorders and oral diseases such as dental caries by promoting dysbiotic biofilm formation and reducing microbial diversity.
Seunghun Han, Kuthirakkal Rajitha, Sungbin Park, Jaeeui Lim, Hee-Young Jung, Junghyun Kim, Junghyun Kim, Dongyeop Kim, Dongyeop Kim   +8 more
doaj   +5 more sources

Toxicological Assessment of D-Allulose From a Novel One-Step Fermentation Process Using Genetically Modified <i>Escherichia coli</i>: A 90-Day Dietary Toxicity Study in Rats. [PDF]

J Toxicol
D‐Allulose is a rare monosaccharide structurally similar to D‐fructose, characterized by low caloric content and relatively high sweetness. This study aimed to conduct a 90‐day oral toxicity test to systemically evaluate the potential toxicological effects of D‐allulose produced via a novel one‐step fermentation process using genetically engineered ...
Li Z, Nie Y, Du H, Zhang W, Zheng S, Cong W, Feng Y, Li G, Jing H, Ning J, Gao S.   +10 more
europepmc   +2 more sources

Review on D-Allulose: In vivo Metabolism, Catalytic Mechanism, Engineering Strain Construction, Bio-Production Technology

Frontiers in Bioengineering and Biotechnology, 2020
Rare sugar D-allulose as a substitute sweetener is produced through the isomerization of D-fructose by D-tagatose 3-epimerases (DTEases) or D-allulose 3-epimerases (DAEases).
Suwei Jiang, Suwei Jiang, Wei Xiao, Xingxing Zhu, Peizhou Yang, Zhi Zheng, Shuhua Lu, Shaotong Jiang, Guochang Zhang, Jingjing Liu   +9 more
doaj   +3 more sources

Correction to "Identification of FGF21-inducing rare sugars that reduces sugar appetite in male BL/6 mice". [PDF]

Physiol Rep
Physiological Reports, Volume 14, Issue 8, April 2026.
europepmc   +2 more sources

Safety evaluation of the food enzyme d-psicose 3-epimerase from the genetically modified <i>Escherichia coli</i> strain K-12 W3110-TKO CDX-088. [PDF]

EFSA J
Abstract The food enzyme d‐psicose 3‐epimerase (EC 5.1.3.30) is produced with the genetically modified Escherichia coli strain K‐12 W3110‐TKO CDX‐088 by Tate & Lyle Ingredients France SAS. The production strain of the food enzyme contains several copies of a known antimicrobial resistance gene. However, based on the absence of viable cells and DNA from
EFSA Panel on Food Enzymes (FEZ), Zorn H, Barat Baviera JM, Bolognesi C, Catania F, Gadermaier G, Greiner R, Mayo B, Mortensen A, Roos YH, Solano MLM, Van Loveren H, Vernis L, Peluso S, Fernández-Fraguas C, Pasch J, Liu Y.   +16 more
europepmc   +2 more sources

Identification of FGF21-inducing rare sugars that reduces sugar appetite in male BL/6 mice. [PDF]

Physiol Rep
Dietary sugars induced FGF21 secretion from the liver and activate hypothalamic oxytocin neurons to reduce furter sugar intake. Replacing obesogenic dietary sugars with FGF21‐inducing rare sugars can stimulate the same system and reduce sugar appetite.
Efendi OGHNB, Matsui S, Tsuzuki S, Sasaki T.   +3 more
europepmc   +2 more sources

LF-NMR for Assessing the Influence of Cryoprotectant Additives on Functional Properties and Feasibility of 3D Printing of Atlantic Cod (Gadus morhua) Surimi. [PDF]

Magn Reson Chem
LF‐NMR assessment of the complex gelling processes of 3D printed surimi from Atlantic cod sidestreams, as affected by different cryoprotectants, was conducted. High‐quality products from sidestreams are necessary for full utilization of the raw material and more sustainable food processing.
Napitupulu RJ, Arason S, Tómasson T, Gudjónsdóttir M.   +3 more
europepmc   +2 more sources

Computational design of allulose-responsive biosensor toolbox for auto-inducible protein expression and CRISPRi mediated dynamic metabolic regulation [PDF]

Nature Communications
Biosensors based on transcription factors (TFs) have shown extensive applications in synthetic biology. Due to the complex multi-domain structure of effector-TF-DNA, computational design of TFs remains a challenge.
Qianzhen Dong, Peng Chen, Zhiru Guo, Hongli Wei, Yan Zeng, Jingyu Zhang, Yan Men, Weidong Liu, Yuanxia Sun, Jiangang Yang   +9 more
doaj   +2 more sources

Construction of hyperthermostable d-allulose 3-epimerase from Arthrobacter globiformis M30 using the sequence information from Arthrobacter psychrolactophilus. [PDF]

FEBS Open Bio
d‐Allulose can be produced from d‐fructose by d‐allulose 3‐epimerase. Based on sequence homology information, we successfully engineered thermostable mutants with the protein engineering method. By integrating positive mutations, we constructed an enzyme that exhibits hyperthermostability without a loss in the activity.
Shimada K, Ohtani K, Gullapalli PK, Ishikawa K.   +3 more
europepmc   +2 more sources

Optimization of fermentation conditions for whole cell catalytic synthesis of D-allulose by engineering Escherichia coli [PDF]

Scientific Reports
D-allulose/D-psicose is a significant rare sugar with broad applications in the pharmaceutical, food, and other industries. In this study, we cloned the D-allulose 3-epimerase (DPEase) gene from Arthrobacter globiformis M30, using pET22b as the vector ...
Haoran Liu, Kang Xu, ShuQi Sun, Yinbiao Wan, Bojia Zhang, Yang Song, Chuanzhuang Guo, Songsen Sui, Ruiming Wang, Piwu Li, Junqing Wang, Zhenshang Xu, Ting Wang   +12 more
doaj   +2 more sources