Results 31 to 40 of about 708 (166)

Teratogenicity of D-allulose

Toxicology Reports, 2022
The objective of this study was to evaluate whether D-allulose has teratogenic effects on rats. A prenatal developmental toxicity test was conducted in SD rats in compliance with modified OECD guidelines test number 414, prenatal developmental toxicity study.
Soonok Sa, Yunji Seol, Albert W. Lee, Yong Heo, Hye-jung Kim, Chong Jin Park   +5 more
openaire   +3 more sources

Recent Advances Regarding the Physiological Functions and Biosynthesis of D-Allulose

Frontiers in Microbiology, 2022
D-Allulose, a generally regarded as safe (GRAS) sugar, is rare in nature. It is among the most promising sweeteners for future use due to its low caloric content, sucrose-like taste, and unique functions.
Zhou Chen, Xiao-Dong Gao, Zijie Li
doaj   +1 more source

Investigation of d-allulose effects on high-sucrose diet-induced insulin resistance via hyperinsulinemic-euglycemic clamps in rats

Heliyon, 2021
d-Allulose, a C-3 epimer of d-fructose, is a rare sugar that has no calories. Although d-allulose has been reported to have several health benefits, such as anti-obesity and anti-diabetic effects, there have been no reports evaluating the effects of d ...
Yukie Natsume, Takako Yamada, Tetsuo Iida, Nobuaki Ozaki, Yang Gou, Yoshiharu Oshida, Teruhiko Koike   +6 more
doaj   +1 more source

Research Advances of d-allulose: An Overview of Physiological Functions, Enzymatic Biotransformation Technologies, and Production Processes

Foods, 2021
d-allulose has a significant application value as a sugar substitute, not only as a food ingredient and dietary supplement, but also with various physiological functions, such as improving insulin resistance, anti-obesity, and regulating glucolipid ...
Yu Xia, Qianqian Cheng, Wanmeng Mu, Xiuyu Hu, Zhen Sun, Yangyu Qiu, Ximing Liu, Zhouping Wang   +7 more
doaj   +1 more source

Allulose for the attenuation of postprandial blood glucose levels in healthy humans: A systematic review and meta-analysis.

PLoS ONE, 2023
D-Allulose is a rare sugar that exists in nature. It is a food ingredient with nearly zero calories (
Yuma Tani, Masaaki Tokuda, Naoki Nishimoto, Hideto Yokoi, Ken Izumori   +4 more
doaj   +3 more sources

Produce D-allulose from non-food biomass by integrating corn stalk hydrolysis with whole-cell catalysis

Frontiers in Bioengineering and Biotechnology, 2023
D-allulose is a high-value rare sugar with many health benefits. D-allulose market demand increased dramatically after approved as generally recognized as safe (GRAS).
Qing Jia, Hui Zhang, Anqi Zhao, Lingbo Qu, Wenlong Xiong, Md. Asraful Alam, Jixing Miao, Weigao Wang, Feihu Li, Feihu Li, Jingliang Xu, Yongkun Lv   +11 more
doaj   +1 more source

Review on D-Allulose: In vivo Metabolism, Catalytic Mechanism, Engineering Strain Construction, Bio-Production Technology

Frontiers in Bioengineering and Biotechnology, 2020
Rare sugar D-allulose as a substitute sweetener is produced through the isomerization of D-fructose by D-tagatose 3-epimerases (DTEases) or D-allulose 3-epimerases (DAEases).
Suwei Jiang, Suwei Jiang, Wei Xiao, Xingxing Zhu, Peizhou Yang, Zhi Zheng, Shuhua Lu, Shaotong Jiang, Guochang Zhang, Jingjing Liu   +9 more
doaj   +1 more source

Metabolically Engineered Escherichia coli for Conversion of D-Fructose to D-Allulose via Phosphorylation-Dephosphorylation

Frontiers in Bioengineering and Biotechnology, 2022
D-Allulose is an ultra-low calorie sweetener with broad market prospects. As an alternative to Izumoring, phosphorylation-dephosphorylation is a promising method for D-allulose synthesis due to its high conversion of substrate, which has been ...
Qiang Guo, Chen-Yang Liu, Ling-Jie Zheng, Shang-He Zheng, Ya-Xing Zhang, Su-Ying Zhao, Su-Ying Zhao, Hui-Dong Zheng, Hui-Dong Zheng, Li-Hai Fan, Li-Hai Fan, Xiao-Cheng Lin   +11 more
doaj   +1 more source

d-Allulose 3-epimerase of Bacillus sp. origin manifests profuse heat‐stability and noteworthy potential of d-fructose epimerization

Microbial Cell Factories, 2021
Background d-Allulose is an ultra-low calorie sugar of multifarious health benefits, including anti-diabetic and anti-obesity potential. d-Allulose 3-epimerase family enzymes catalyze biosynthesis of d-allulose via epimerization of d-fructose.
Satya Narayan Patel, Girija Kaushal, Sudhir P. Singh   +2 more
doaj   +1 more source

Construction and Optimization of Biosynthetic Pathway for the Production of D-Allulose from Glucose in Escherichia coli [PDF]

Shipin Kexue
A pathway in Escherichia coli BL21 (DE3) was constructed to produce D-allulose from D-glucose via a phosphorylation-dephosphorylation strategy. The genes related to competitive pathways were deleted using the CRISPR/Cas9 system, and allulose-6-phosphate
JIANG Yawen, ZHANG Cangping, YANG Shaoqing, JIANG Zhengqiang, LI Yanxiao, YAN Qiaojuan
doaj   +1 more source