Results 41 to 50 of about 2,707 (305)

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

Construction and Testing of a Rarefied Gas Flow Facility [PDF]

, 1967
A low-density gasdynamic facility, suitable for measurement of mass flow through small (approximately 1 mm diameter) nozzles, tubes, and orifices, was designed and constructed. The system is capable of producing and measuring mass flows at 100:1 upstream/
Henderson, Arnold Herbert, Henderson, Arnold H.   +1 more
core   +1 more source

Editorial: Rarefied Gas Flows—From Micro–Nano Scale to the Hypersonic Regime

Fluids
Rarefied gas dynamics spans a wide spectrum of applications: micro–nano devices where the mean free path becomes comparable to characteristic lengths, vacuum and porous systems where Knudsen diffusion emerges, and high-speed (including hypersonic) flows ...
Ehsan Roohi
doaj   +1 more source

Rarefied Flow Simulation of Conical Intake and Plasma Thruster for Very Low Earth Orbit Spaceflight

Frontiers in Physics, 2022
Air-breathing electric propulsion has the potential to enable space missions at very low altitudes. This study introduces to a 0D hybrid formulation for describing the coupled intake and thruster physics of an air-breathing electric propulsion prototype.
Eugenio Ferrato, Eugenio Ferrato, Vittorio Giannetti, Vittorio Giannetti, Mansur Tisaev, Andrea Lucca Fabris, Francesco Califano, Tommaso Andreussi, Tommaso Andreussi   +8 more
doaj   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

On the Lightweight Potential of Laser Additive Manufactured NiTi Triply Periodic Minimal Sheet Lattices

Advanced Engineering Materials, EarlyView.
This study explores the lightweight potential of laser additive‐manufactured NiTi triply periodic minimal surface sheet lattices. It systematically investigates the effects of relative density and unit cell size on surface quality, deformation recovery, compression behavior, and energy absorption.
Haoming Mo, Shuo Qu, Shiming Gao, Xu Song   +3 more
wiley   +1 more source

Validation of a hybrid grid scheme of DSMC in simulating three-dimensional rarefied gas flows [PDF]

, 2003
A hybrid grid scheme is employed in a new version of position element algorithm of the direct simulation Monte Carlo (DSMC) method. The computational domain is divided into uniform rectangular grids to track molecular trajectories efficiently, whereas ...
Liu, HL (reprint author), Chinese Acad Sci, Inst Mech, Lab High Temp Gas Dynam, Beijing 100080, Peoples R China., 沈青, 樊菁, 刘宏立   +3 more
core  

Rarefied Gas Flow through Porous Media: Experiments and Numerical Simulation [PDF]

, 2012
In this paper we present the results of an experimental analysis concerning non-isothermal gas flow through a porous medium made of a packed bed of spheres.
E. Afrasiabian, C. M. Casciola, CASCIOLA, Carlo Massimo, Afrasiabian, E, L. Marino, Marino, L, Casciola, CM, MARINO, Luca   +7 more
core   +1 more source

Thermodynamic Pathways of Nonequilibrium Solidification in Wire‐Arc Additive Manufacturing Fe‐Based Multicomponent Alloy Structures

Advanced Engineering Materials, EarlyView.
Geometry‐driven thermal behavior in wire‐arc additive manufacturing (WAAM) influences microstructural evolution during nonequilibrium solidification of a chemically complex Fe–Cr–Nb–W–Mo–C nanocomposite system. By comparing different deposits configurations, distinct entropy–cooling rate correlations, segregation, and carbide evolution are revealed ...
Blanca Palacios, Anthony Gonzalez, Aleksander Aleman, Tyler Dolmetsch, Tanaji Paul, Arvind Agarwal   +5 more
wiley   +1 more source