Results 201 to 210 of about 359,204 (269)

Lactylation of Mutation-Prone RAS Residues Mimics Oncogenic Mutations and Drives Constitutive Activation. [PDF]

Cancer Commun (Lond)
Liao R, Ma C, Chen X, Bai L, Cao Q, Zhang Y, Dong C.   +6 more
europepmc   +1 more source

In Situ Bioorthogonal Synthesis of PROTACs via Dual‐Responsive Cleavage for Synergistic Photo‐Immunotherapy

Advanced Science, EarlyView.
A bioactive self‐delivering SNAP‐TAC platform responds to tumor‐associated cathepsin B and glutathione, enabling in situ bioorthogonal synthesis of a BRD4‐degrading proteolysis‐targeting chimera within the tumor microenvironment. The resulting BRD4 degradation and PD‐L1 downregulation synergize with photodynamic therapy‐induced immunogenic cell death ...
Shiqin Jian, Jiasha Wu, Fusheng Xu, Yan Zuo, Huaxing Shen, Rui Ji, Luyi Wang, Na Li, Yanting Sun, Yongsheng Yu, Yejiao Shi, Honggang Hu, Feng Xu, Dan Huang, Xiaochun Hu   +14 more
wiley   +1 more source

Effect of GLP-1 receptor agonist on nutrient intake: A narrative review. [PDF]

Nutr Clin Pract
Fujioka K.
europepmc   +1 more source

Thermal Shifts Dominate Single‐Gene Responses to Transcription‐Targeting Antibiotics

Advanced Science, EarlyView.
Thermal shifts reshape bacterial responses to transcription‐targeting antibiotics. In E. coli, temperature can dominate antibiotic‐induced genome‐wide expression, particularly outside 30°C–39°C, through changes in adenosine triphosphate (ATP), nucleoid organization, and drug‐target engagement.
Rahul Jagadeesan, Amir M. Arsh, Vatsala Chauhan, Suchintak Dash, Pooja Ravaria, Andre S. Ribeiro   +5 more
wiley   +1 more source

The Benign COMPARE Study: Comparing Perioperative Outcomes of Benign Minimally Invasive Laparoscopic, da Vinci Robotic, and Open Procedures: A Systematic Review and Meta-Analysis of Evidence. [PDF]

Ann Surg Open
Shin TH, Ricciardi R, Seshadri-Kreaden U, Mathur M, Cantrell LA, Yankovsky A, Greene K, Patel NM, Hebert AE, Hallowell PT.   +9 more
europepmc   +1 more source

Exotic clustering in Ra-222,Ra-224,Ra-226

, 2016
Buck, B, Merchant, A, Perez, S
openaire   +1 more source

Engineered Peptide Self‐Assembled Nanofibers for Enhanced STING Activation: A Promising Nanodelivery Platform for Immunotherapy of Pediatric Solid Tumors

Advanced Science, EarlyView.
An engineered peptide self‐assembled nanofiber platform, designed to replicate STING–cGAMP binding motifs, facilitates pH‐responsive cytosolic delivery of cGAMP, enhances the endoplasmic reticulum with high efficiency, and robustly activates the STING pathway.
Yubin He, Xiao Lu, Chang qing Yang, Ran Zhang, Bo Wan, Xin Ni, Dong Mei   +6 more
wiley   +1 more source

Health technology assessment of robotic surgery for rectal cancer in China: protocol for a nationally multicentre prospective cohort study. [PDF]

BMJ Open
Lyu B, Cai Z, Feng Q, Cai S, Zhou YB, Liu Q, Wang G, Wang M, Ye Y, Li T, Dai S, Yuan W, Huang Y, Xia L, Shi Y, Jia B, Li T, He Z, Wu Z, Zhan H, Hu X, Wang J, Xu J, Wu X, Liu GG, SMART study group.   +25 more
europepmc   +1 more source

The Prevalence of Variations in the Morphology of Renal Arteries in the North Indian Population. [PDF]

Cureus
Bashri R, Singh R.
europepmc   +1 more source